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Article Abstract
This study aimed to validate a combination of , and CA724 for gastric cancer (GC) detection. The performance of , and CA724 was examined in a prospective cohort study with 518 participants (151 with GC, 56 with atrophic gastritis, 87 with other gastrointestinal diseases and 224 with no evidence of disease). , or CA724 alone detected 48.3, 37.1 and 43.1% of GC, respectively. The combination of and detected 60.3% of GC, and the combination of all three markers detected 68.6% of GC. The detection sensitivity of and was significantly higher for gastric body and in elder subjects. was correlated with poorer GC survival. The combination of , and CA724 was adequately sensitive for GC detection. The blood was predictive for GC prognosis.
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| http://dx.doi.org/10.2217/epi-2021-0080 | DOI Listing |
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