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Twin-field quantum key distribution (TF-QKD) has attracted considerable attention and developed rapidly due to its ability to surpass the fundamental rate-distance limit of QKD. However, the device imperfections may compromise its practical implementations. The goal of this paper is to make it robust against the state preparation flaws (SPFs) and side channels at the light source. We adopt the sending or not-sending (SNS) TF-QKD protocol to accommodate the SPFs and multiple optical modes in the emitted states. We analyze that the flaws of the phase modulation can be overcome by regarding the deviation of the phase as phase noise and eliminating it with the post-selection of phase. To overcome the side channels, we extend the generalized loss-tolerant (GLT) method to the four-intensity decoy-state SNS protocol. Remarkably, by decomposing of the two-mode single-photon states, the phase error rate can be estimated with only four parameters. The practical security of the SNS protocol with flawed and leaky source can be guaranteed. Our results might constitute a crucial step towards guaranteeing the practical implementation of the SNS protocol.
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http://dx.doi.org/10.3390/e23091103 | DOI Listing |
Dev Psychobiol
September 2025
Department of Human Development and Family Science, Auburn University, Auburn, Alabama, USA.
The present study sought to build on prior research by examining within-system (sympathetic nervous system [SNS] × SNS) and cross-system (SNS × parasympathetic nervous system [PNS]) interactions between measures of autonomic reactivity to social stress as predictors of anxiety. The physiological responses (respiratory sinus arrhythmia [RSA], skin conductance level [SCL], and pre-ejection period [PEP]) of 123 preadolescents (Mage = 12.03 years) were measured continuously during a lab protocol designed to simulate common peer evaluation experiences.
View Article and Find Full Text PDFJMIR Public Health Surveill
August 2025
School of Medicine, University of North Carolina at Chapel Hill, 130 Mason Farm Rd, Chapel Hill, NC, 27599-6134, United States, 1 9199662536.
Background: In the United States, persisting new HIV diagnoses among gay, bisexual, and other cisgender men who have sex with men (GBMSM) and transgender women make it unlikely that the United States will meet the Ending the HIV Epidemic's (EHE) goal to reduce new HIV diagnoses by 90% by 2030. Innovative strategies are needed to address this challenge, particularly in the US South, where Black and Latinx GBMSM and transgender women are disproportionately impacted by HIV. Social network approaches have led to increased HIV testing uptake.
View Article and Find Full Text PDFNanoscale Adv
August 2025
NEST Laboratory, Scuola Normale Superiore Piazza San Silvestro 12 56127 Pisa Italy
Poly(α-glutamic acid) (PGA)-based nanogels (NGs) have garnered significant attention due to their biocompatibility, biodegradability, and potential to be functionalized. Recent advances in click chemistry, particularly strain-promoted azide-alkyne cycloaddition (SPAAC), enable the formation of nanogels under mild, metal-free conditions, preserving biocompatibility and avoiding contamination. In this work, we developed and optimized a protocol based on SPAAC click chemistry for the production of PGA-based NGs; moreover, we investigated their physicochemical properties, stability, and potential for drug delivery by encapsulating doxorubicin (Dox) as a model drug.
View Article and Find Full Text PDFMagn Reson Med
August 2025
Laboratory for Social and Neural Systems Research (SNS Lab), University of Zurich, Zurich, Switzerland.
Purpose: The aim of the presented work is to develop a diffusion instability measure (DIM) that can be used in quality assurance.
Methods: Single-shot, spin-echo, echo-planar imaging HARDI diffusion data sets were collected on a spherical silicone oil phantom with 64 different diffusion directions on a 3T Philips Achieva and a 3T Siemens Cima.X scanner with similar acquisition protocols.
Int J Colorectal Dis
August 2025
Nursing Department, Shanxi Province Cancer Hospital/Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences/Cancer Hospital Affiliated to Shanxi Medical University, Taiyuan, Shanxi Province, China.
Purpose: The purpose of this umbrella review was to systematically evaluate the effectiveness of therapeutic strategies for managing low anterior resection syndrome following sphincter-preserving surgery for rectal cancer and to provide evidence-based recommendations for clinical practice.
Methods: A systematic literature search was performed across five electronic databases. Two independent reviewers screened titles/abstracts, assessed full-text studies, and extracted data, with discrepancies resolved by consensus.