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pneumonia (PCP) is one of the most common opportunistic infections in HIV-infected patients. However, coinfection with is infrequent in AIDS patients with PCP. We report a 28-year-old male AIDS patient coinfected with and diagnosed in the bronchoalveolar lavage. After sulfamethoxazole-trimethoprim and meropenem treatment, the patient showed clinical improvement in 2 weeks. Clinicians need to be alert to the occurrence of infection in AIDS patients with PCP and timely diagnosis and antibacterial treatments are essential. This case may help clinicians for timely diagnosis of the coinfection of and in AIDS patients.
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http://dx.doi.org/10.3389/fpubh.2021.663093 | DOI Listing |
Patient
September 2025
PPD Evidera Patient-Centered Research, Thermo Fisher Scientific, Waltham, MA, USA.
Background: Migraine care is often suboptimal owing to undertreatment, variation in clinical outcomes and administration methods among existing treatments, and between- and within-individual heterogeneity in the clinical course of migraine. In response to these challenges, preference studies have been increasingly conducted to inform treatment decision-making and development. However, gaps remain in understanding how treatment preferences have been assessed across different migraine studies.
View Article and Find Full Text PDFTrauma Surg Acute Care Open
September 2025
Medical Center of the Rockies, Loveland, Colorado, USA.
Introduction: Efforts to strengthen healthcare systems have led to the development of clinical practice guidance, defined as clinical decision-making aids built on scientific evidence, experiential knowledge, and ideally, patient values. This review evaluates the accessibility, relevance, and quality of existing trauma guidance globally.
Methods: A systematic review evaluated trauma-related clinical guidance sources published from 2016 to 2023, searching in English across eight databases and 28 professional society websites.
Trauma Surg Acute Care Open
September 2025
UCHealth, Loveland, Colorado, USA.
Introduction: Trauma clinical guidance (guidelines, protocols, algorithms, etc) has been shown to improve patient outcomes; however, it is only used in about half of the patients to whom it applies. Guidance implementation is affected by intrinsic factors (eg, guidance format) as well as extrinsic factors (eg, the clinical environment). Recommendations and frameworks have been created to aid in the development of implementable guidance.
View Article and Find Full Text PDFKaposi sarcoma (KS) is an angioproliferative malignancy associated with human herpesvirus 8 (HHV-8) infection, predominantly affecting immunocompromised patients such as those with HIV/AIDS. Despite advances in antiretroviral therapy, KS remains a significant cause of morbidity and mortality in this population, especially when diagnosis or treatment is delayed. Ocular involvement, although rare, can lead to significant functional impairment.
View Article and Find Full Text PDFLancet Reg Health West Pac
August 2025
Global HIV, Hepatitis and STI Programmes, World Health Organization (WHO), Geneva, Switzerland.
Background: The global spread of antimicrobial resistance (AMR) in threatens empiric single-dose gonorrhoea treatment. Enhanced global AMR surveillance is imperative. We report i) gonococcal antimicrobial susceptibility and resistance data from 2023 in the World Health Organization Enhanced Gonococcal Antimicrobial Surveillance Programme (WHO EGASP) in the WHO Western Pacific Region (Cambodia, the Philippines, Viet Nam), Southeast Asian Region (Indonesia, Thailand), and African Region (Malawi, South Africa, Uganda, Zimbabwe), and ii) metadata of the gonorrhoea patients.
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