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The visual system is capable of recognizing objects when object information is widely separated in space, as revealed by the Kanizsa-type illusory contours (ICs). Attentional involvement in perception of ICs is an important topic, and the present study examined whether and how the processing of ICs is interfered with by a distractor. Discrimination between thin and short deformations of an illusory circle was investigated in the absence or presence of a central dynamic patch, with difficulty of discrimination varied in three levels (easy, medium, and hard). Reaction time (RT) was significantly shorter in the absence compared to the presence of the distractor in the easy and medium conditions. Correct rate (CR) was significantly higher in the absence compared to the presence of the distractor in the easy condition, and the magnitude of the difference between CRs of distracted and non-distracted responses significantly reduced as task difficulty increased. These results suggested that perception of ICs is more likely to be vulnerable to distraction when more attentional resources remain available. The present finding supports that attention is engaged in perception of ICs and that distraction of IC processing is associated with perceptual load.
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http://dx.doi.org/10.3389/fpsyg.2021.526972 | DOI Listing |
Glob Health Action
December 2025
Molecular Ecology, UK Centre for Ecology and Hydrology, Wallingford, UK.
Background: Antimicrobial resistance (AMR) in the environment is an important component of One Health AMR research and is increasingly incorporated into AMR National Action Plans (NAPs), including the UK's AMR NAP 'Tackling antimicrobial resistance 2019-2024'. However, implementation of the environmental commitments has yet to be evaluated.
Objective: In this study, we aimed to understand UK stakeholder perspectives on the delivery and implementation of the environmental components of the UK's AMR NAP 2019-2024, with a particular focus on wastewater, which could be used to inform the 2024-2029 NAP.
BMC Nephrol
August 2025
Disease, Cardiovascular Risk, and Lifestyle in Primary Health Care (MARCEVAP) Research Group, Fundació Institut Universitari per a la recerca a l'Atenció Primària (IDIAPJGol), L'Hospitalet Llobregat, Barcelona, Spain.
Background: Although evidence has demonstrated the influence of perceptions of chronic kidney disease on health outcomes in patients, there are still gaps in our knowledge regarding how such perceptions manifest themselves in specific populations with advanced chronic kidney disease (ACKD). This study aims to investigate the cognitive and emotional processes of people with ACKD in relation to their illness, as well as to examine their coping strategies and experiences of care in the context of outpatient care in the southern metropolitan area of Barcelona (Spain).
Methods: This is a qualitative study in which the lived experiences and perceptions of ACKD are explored based on the postulates of the Self-Regulation Model (SRM).
J Vis
August 2025
State Key Laboratory of Cognitive Science and Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China.
The (co)representation of time and numerosity has long been a topic of enduring interest. While a theory of magnitude (ATOM) posits that these dimensions are governed by a shared representational system, empirical findings offer both supporting and conflicting evidence. Previous challenging research has highlighted that time and numerosity perception can be distorted in opposite directions by explicitly introducing emotional or cognitive interference.
View Article and Find Full Text PDFBr J Psychiatry
July 2025
Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK.
Background: Targeting the glutamatergic system is posited as a potentially novel therapeutic strategy for psychotic disorders. While studies in subjects indicate that antipsychotic medication reduces brain glutamatergic measures, they were unable to disambiguate clinical changes from drug effects.
Aims: To address this, we investigated the effects of a dopamine D2 receptor partial agonist (aripiprazole) and a dopamine D2 receptor antagonist (amisulpride) on glutamatergic metabolites in the anterior cingulate cortex (ACC), striatum and thalamus in healthy controls.
Mol Psychiatry
July 2025
Department of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Dopamine D2/D3 receptor modulation with antipsychotics is thought to affect cognitive function, but causal evidence in humans is scant, and largely limited to single administrations. Clarifying this is of importance given the widespread use of antipsychotics, and to understand the role of D2/D3 signalling in human cognition. We therefore conducted a double-blind, placebo-controlled crossover study following sustained administration of either a dopamine D2/D3 receptor antagonist (amisulpride at 400 mg daily) or a D2/D3 partial agonist (aripiprazole at 10 mg daily) to two separate samples of healthy humans (total n = 50) for 7 days per condition.
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