Host defense peptides identified in human apolipoprotein B as novel food biopreservatives and active coating components.

Food Microbiol

Department of Chemical Sciences, University of Naples Federico II, Via Cintia 21, 80126, Naples, Italy; Istituto Nazionale di Biostrutture e Biosistemi (INBB), Rome, Italy. Electronic address:

Published: October 2021


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Article Abstract

The effectiveness of three novel "host defence peptides" identified in human Apolipoprotein B (ApoB) as novel antimicrobial and antibiofilm agents to be employed in food industry is reported. ApoB-derived peptides have been found to exert significant antimicrobial effects towards Salmonella typhimurium ATCC® 14028 and Salmonella enteritidis 706 RIVM strains. Furthermore, they have been found to retain antimicrobial activity under experimental conditions selected to simulate those occurring during food storage, transportation and heat treatment, and have been found to be endowed with antibiofilm properties. Based on these findings, to evaluate the applicability of ApoB-derived peptides as food biopreservatives, coating solutions composed by chitosan (CH) and an ApoB-derived peptide have been prepared and found to be able to prevent Salmonella cells attachment to different kinds of surfaces employed in food industry. Finally, obtained coating solution has been demonstrated to hinder microbial proliferation in chicken meat samples. Altogether, obtained findings indicate that ApoB-derived peptides are promising candidates as novel biopreservatives for food packaging.

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http://dx.doi.org/10.1016/j.fm.2021.103804DOI Listing

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Host defense peptides identified in human apolipoprotein B as novel food biopreservatives and active coating components.

Food Microbiol

October 2021

Department of Chemical Sciences, University of Naples Federico II, Via Cintia 21, 80126, Naples, Italy; Istituto Nazionale di Biostrutture e Biosistemi (INBB), Rome, Italy. Electronic address:

The effectiveness of three novel "host defence peptides" identified in human Apolipoprotein B (ApoB) as novel antimicrobial and antibiofilm agents to be employed in food industry is reported. ApoB-derived peptides have been found to exert significant antimicrobial effects towards Salmonella typhimurium ATCC® 14028 and Salmonella enteritidis 706 RIVM strains. Furthermore, they have been found to retain antimicrobial activity under experimental conditions selected to simulate those occurring during food storage, transportation and heat treatment, and have been found to be endowed with antibiofilm properties.

View Article and Find Full Text PDF