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Grapevine fanleaf disease, caused by grapevine fanleaf virus (GFLV), transmitted by the soil-borne nematode Xiphinema index, provokes severe symptoms and economic losses, threatening vineyards worldwide. As no effective solution exists so far to control grapevine fanleaf disease in an environmentally friendly way, we investigated the presence of resistance to GFLV in grapevine genetic resources. We discovered that the Riesling variety displays resistance to GFLV, although it is susceptible to X. index. This resistance is determined by a single recessive factor located on grapevine chromosome 1, which we have named rgflv1. The discovery of rgflv1 paves the way for the first effective and environmentally friendly solution to control grapevine fanleaf disease through the development of new GFLV-resistant grapevine rootstocks, which was hitherto an unthinkable prospect. Moreover, rgflv1 is putatively distinct from the virus susceptibility factors already described in plants.
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http://dx.doi.org/10.1038/s42003-021-02164-4 | DOI Listing |
Virologie (Montrouge)
June 2025
Plant Pathology and Plant-Microbe Biology, School of Integrative Plant Science, Cornell University, Geneva, NY 14456, USA.
Fanleaf degeneration disease is referred to as "ortiage" in the French literature in 1723. Nowadays it occurs in most vineyards worldwide. Grapevine fanleaf virus (GFLV) is the main causal agent of the disease.
View Article and Find Full Text PDFPhytopathology
September 2025
Section of Plant Pathology and Plant-Microbe Biology, School of Integrative Plant Science, Cornell University, Cornell AgriTech, Geneva, NY 14456, U.S.A.
Grapevine fanleaf virus (GFLV) is the main causative agent of fanleaf degeneration disease. Transmission of GFLV is exclusively accomplished by the ectoparasitic dagger nematode in a noncirculative, nonpropagative mode. Previous studies of GFLV-host interactions revealed strain- and viral amino acid-specific changes to the root system architecture (RSA) in .
View Article and Find Full Text PDFFront Microbiol
August 2024
Plant Pathology and Plant-Microbe Biology Section, School of Integrative Plant Science College of Agriculture and Life Sciences, Cornell University, Cornell AgriTech at the New York State Agricultural Experiment Station, Geneva, NY, United States.
Viral suppressors of RNA silencing (VSRs) encoded by grapevine fanleaf virus (GFLV), one of the most economically consequential viruses of grapevine ( spp.), were recently identified. GFLV VSRs include the RNA1-encoded protein 1A and the putative helicase protein 1B, as well as their fused form (1AB).
View Article and Find Full Text PDFFunct Plant Biol
July 2024
College of Life Science and Technology, Gansu Agricultural University, Lanzhou 730070, China; and College of Horticulture, Gansu Agricultural University, Lanzhou 730070, China; and Laboratory of Aridland Crop Science, Gansu Agricultural University, Lanzhou 730070, China.
The WUSCHEL-related homeobox (WOX) transcription factor family plays critical roles in plant growth, development, and stress adaptation, but the biological functions in response to various stress of the WOX gene family have not been extensively researched in grapevine (Vitis vinifera ). In this study, 12 grapevine WOXs were identified from the grapevine genome. Quantitative PCR and microarray expression profiling found that the expression of WOXs had an obvious tissue-specific pattern.
View Article and Find Full Text PDFBMC Microbiol
July 2024
Plant Pathology and Plant-Microbe Biology Section, Cornell University, Cornell AgriTech at the New York State Agricultural Experiment Station, Geneva, NY, 14456, USA.
Background: Grapevine fanleaf virus (GFLV) is one of the most detrimental viral pathogens of grapevines worldwide but no information is available on its effect on the root system architecture (RSA) of plant hosts. We used two wildtype GFLV strains and their single amino acid mutants to assess RSA traits in infected Nicotiana benthamiana and evaluate transcriptomic changes in host root gene expression in replicated time course 3'RNA-Seq experiments. Mutations targeted the multi-functional GFLV-encoded protein 1E, a putative RNA-dependent RNA polymerase and determinant of foliar symptoms in N.
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