Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8108984 | PMC |
| http://dx.doi.org/10.3389/fcimb.2021.670677 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Snapshot of Defense Systems in Multidrug Resistant .
MicroPubl Biol
August 2025
West African Centre for Cell Biology of Infectious Pathogens, Department of Biochemistry, Cell and Molecular Biology, College of Basic and Applied Sciences, University of Ghana, P. O. Box LG54, Legon, Accra, Ghana.
Bacterial defense mechanisms protect pathogens from host immunity, bacteriophages, and harsh environments. This study investigates defense systems in multidrug-resistant from Ghanaian hospital ICUs, focusing on CRISPR-Cas, restriction-modification (R-M), and toxin-antitoxin (TA) systems. Genomes of environmental (NS2) and clinical (PS4) strains were sequenced and analyzed using PADLOC, defensefinder, and TADB3.
View Article and Find Full Text PDFThe effect of yeaZ on formation and resuscitation of viable but nonculturable (VBNC) Salmonella enteritidis serovar enteritidis.
Food Microbiol
January 2026
Yantai Key Laboratory of Animal Pathogenetic Microbiology and Immunology, School of Life Sciences, Ludong University, Yantai, 264025, Shandong, China. Electronic address:
The presence of Salmonella species cells in the viable but nonculturable (VBNC) state has been extensively confirmed in both aqueous environments and food systems, posing a significant and often underestimated threat to public health. However, the regulatory mechanisms governing the formation and resuscitation of VBNC Salmonella remain incompletely understood. This study aimed to elucidate the functions of yeaZ in regulating the formation and resuscitation of VBNC Salmonella enteritidis.
View Article and Find Full Text PDFLocus Displays Features of a Type I Toxin-Antitoxin System.
Toxins (Basel)
July 2025
Department of Chemistry and Biochemistry, Faculty of Chemistry and Chemical Technology, University of Ljubljana, Večna pot 113, 1000 Ljubljana, Slovenia.
Type I toxin-antitoxin (TA) systems consist of a protein toxin that exerts a cytostatic or cytotoxic effect and an antisense RNA antitoxin that prevents translation of the toxin. Although well studied, type I TA systems have so far only been discovered in bacteria from the phyla Proteobacteria, Firmicutes, and Tenericutes. We hypothesized that type I systems could also be present in Cyanobacteria.
View Article and Find Full Text PDFGenetic determinants of pOXA-48 plasmid maintenance and propagation in Escherichia coli.
Nat Commun
August 2025
Microbiologie Moléculaire et Biochimie Structurale (MMSB), Université Lyon 1, CNRS, Inserm, UMR5086, Lyon, France.
Conjugative plasmids are the main drivers of antibiotic resistance dissemination contributing to the emergence and extensive spread of multidrug resistance clinical bacterial pathogens. pOXA-48 plasmids, belonging to the IncL group, emerge as the primary vehicle for carbapenem resistance in Enterobacteriaceae. Despite the problematic prevalence of pOXA-48, most research focus on epidemiology and genomics, leaving gaps in our understanding of the mechanisms behind its propagation.
View Article and Find Full Text PDFDeciphering the RNA-based regulation mechanism of the phage-encoded AbiF system in Clostridioides difficile.
PLoS Genet
August 2025
Université Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Gif-sur-Yvette, France.
Clostridioides difficile is the major cause of nosocomial infections associated with antibiotic therapy. The severity of C. difficile infections increased worldwide with the emergence of hypervirulent strains, including 027 ribotype epidemic strains.
View Article and Find Full Text PDF