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Study Design: Retrospective study.
Objective: Proximal junctional failure (PJF) commonly occurs as a recognized potential outcome of fusion surgery. Here we describe a unique series of patients with multilevel spine fusion including the cervical spine, who developed PJF as an odontoid fracture.
Methods: We performed a single site retrospective review of patients with prior fusion that included a cervical component, who presented with an odontoid fracture between 2012 and 2019. Radiographic measurements included C2-C7 SVA, C2-C7 lordosis, T1 slope, Occiput-C2 angle, proximal junctional kyphosis, and cervical mismatch. Associated fractures, medical comorbidities, and treatments were determined via chart review after IRB approval.
Results: Nine patients met inclusion criteria. 5 reported trauma with subsequent onset of pain. All patients sustained a Type II odontoid fracture. 5 with associated C1/Jefferson fractures. In all patients, pre-injury Occiput-C2 angle was outside normative range; C2-C7 SVA was greater than 4 cm in 6 patients; T1-slope minus cervical lordosis was greater than 18.5 degrees in 6 patients. 7 patients were treated operatively with extension of fusion to C1 and 2 patients declined operative treatment.
Conclusion: In this series of 9 patients with multilevel fusion with type II odontoid fractures, all patients demonstrated abnormal pre-fracture sagittal alignment parameters and a greater than normal association of C1 fractures was noted. Further study is needed to establish the role of poor sagittal alignment with compensatory occiput-C2 angulation as a predisposing factor for odontoid fracture as a proximal junctional failure mechanism.
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http://dx.doi.org/10.1177/21925682211008833 | DOI Listing |
J Orthop
December 2025
University of Pennsylvania, Department of Orthopedic Surgery, Philadelphia, PA, USA.
Introduction: The optimal surgical strategy for managing odontoid fractures in geriatric populations remains controversial, especially regarding the trade-offs between nonunion risk, perioperative complications, and long-term morbidity. This study aimed to compare postoperative outcomes between anterior odontoid fixation and posterior C1-C2 fusion approaches in older adults.
Methods: Using the TriNetX Diamond Network, we retrospectively identified patients aged ≥65 years who underwent anterior vs posterior cervical fixation for odontoid fractures from 2007 to 2023.
Spine J
August 2025
From the Department of Orthopedics, Shanghai Changzheng Hospital, Naval Medical University, Shanghai, People's Republic of China.. Electronic address:
Background Context: Both the intermuscular dissection approach and the midline, standard muscle stripping approach in posterior reduction and temporary fixation (PRTF) technique can effectively avoid the loss of atlantoaxial motion function caused by posterior atlantoaxial fusion. The intermuscular dissection approach demonstrates superior paravertebral muscles integrity preservation. Therefore, we hypothesize that: the range of motion (ROM) in rotation of C1-C2 after instrumentation removal would be superior in patients undergoing PRTF through the intermuscular dissection approach compared to the muscle stripping approach.
View Article and Find Full Text PDFCureus
July 2025
Centre for Spinal Studies and Surgery (CSSS) Queen's Medical Centre, Nottingham University Hospitals, Nottingham, GBR.
This review evaluates anterior, posterior, and combined fixation techniques for pediatric odontoid fractures, addressing the lack of comparative data on outcomes and complications. A Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA)-based review identified 1,497 studies, with eight meeting inclusion criteria after screening. Studies were assessed for quality using the Joanna Briggs Institute checklist, and data on demographics, fracture types, surgical techniques, fusion rates, and complications were analyzed.
View Article and Find Full Text PDFClin Spine Surg
August 2025
Department of Orthopaedic Surgery, Division of Spine Surgery, Walter Reed National Military Medical Center, Bethesda, MD.
Study Design: Retrospective cohort study.
Objective: The purpose of this study is to investigate patterns of surgical treatment of nondisplaced type II odontoid fractures.
Summary Of Background Data: Odontoid fractures represent ∼1/3 of all cervical spine fractures, resulting from low-energy mechanisms in the elderly.
Asian Spine J
August 2025
Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.
Study Design: Retrospective cohort study.
Purpose: We assessed the predisposition to type II odontoid fractures (T2OFs) in elderly people by comparing patients who had T2OFs with those who had sub-axial fractures.
Overview Of Literature: T2OFs are common among elderly people; osteoporosis and degenerative changes in the upper cervical spine are major risk factors.