Publications by authors named "Conor McCarthy"

Study Design: Retrospective cohort study.

Objective: The purpose of this study is to investigate patterns of surgical treatment of nondisplaced type II odontoid fractures.

Summary Of Background Data: Odontoid fractures represent ∼1/3 of all cervical spine fractures, resulting from low-energy mechanisms in the elderly.

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Objectives: To compare the ultimate and relative failure loads of the femoral neck after insertion of a reconstruction nail through either the central collinear start point or the piriformis start point.

Methods: Twelve bilateral cadaveric femur pairs were assigned to either the central collinear (CC) group or the piriformis fossa (PF) group with an effort to match age distribution, sex, and bone mineral density between the 2 groups. All left femora were used as the surgical specimen, and all right femora were used as their respective intact controls.

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Introduction: Lateral clavicle fractures comprise a minority of all clavicle fractures and are associated with high rates of nonunion when managed nonoperatively. Various fixation methods have been described, including augmentation with coracoclavicular (CC) ligament repair or reconstruction. Outcomes following the surgical treatment of lateral clavicle fractures are limited to small case series and systematic reviews, and the literature within physically demanding populations remains sparse.

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Background: Despite clinical evidence of risks in knee arthrofibrosis and graft impingement with larger grafts, the optimal size for quadriceps tendon (QT) autografts in anterior cruciate ligament reconstruction (ACLR) has not been established.

Purpose/hypothesis: This study aimed to evaluate the mechanical properties of full-thickness 6-mm and 8-mm wide QT grafts compared with 10-mm patellar tendon (PT) and 10-mm QT grafts. The hypothesis was that both the 6- and 8-mm QT grafts would exhibit similar or superior ultimate tensile strength compared with the 10-mm PT graft.

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Introduction: As illustrated by the "Walker Dip," there is growing concern regarding the lack of combat casualty care during peacetime. Surgical volume and case complexity are paramount for training and skill sustainment. We sought to quantify the recent orthopedic trauma surgical case load of all military orthopedic surgeons across the Military Health System (MHS).

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Article Synopsis
  • Meniscal injuries are prevalent, and even with advanced repair methods, the success rates are still quite low.
  • New treatments involving biologics show promise, but there is not enough solid evidence on their effectiveness for meniscal healing.
  • This text discusses a method of using amniotic tissue, specifically umbilical cord allograft, in repairing meniscal tears to possibly improve healing outcomes.
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Background: Osteoarthritis (OA) is characterised by the failure of normal biological processes to repair following damage. Traditionally, OA was considered a "wear and tear" disorder; however, it is now a recognised inflammatory condition, preceded by molecular modifications. The aim of this study was to evaluate inflammatory markers among individuals with early knee OA (eKOA) and well-matched asymptomatic controls.

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Introduction: Pelvic asymmetry has been noted in pelvic imaging, and might influence the development of various spinal pathologies, most notably scoliosis. There is a limited understanding of the relationship between pelvic asymmetry and sex and ancestry, and limited use of 3D modeling. The purpose of this study was to identify pelvic asymmetry and morphology differences between sex and ancestry utilizing 3D modeling on young adults in an osteological collection.

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Semiconductor nanocrystals (NCs) with high elemental and structural complexity can be engineered to tailor for electronic, photovoltaic, thermoelectric, and battery applications etc. However, this greater complexity causes ambiguity in the atomic structure understanding. This in turn hinders the mechanistic studies of nucleation and growth, the theoretical calculations of functional properties, and the capability to extend functional design across complementary semiconductor nanocrystals.

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Article Synopsis
  • Blast-related traumatic heterotopic ossification (tHO) leads to complications in healing and quality of life for combat-injured patients, especially those with burns.
  • A study using a rat model showed that adding a thermal burn to pre-existing blast injuries significantly increased the volume of tHO.
  • The research revealed that the combined effects of blast overpressure and burn injuries exacerbate pro-inflammatory responses, highlighting the need for better understanding and treatment of such injuries in combat scenarios.
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Introduction: Heterotopic ossification (HO) is a complex pathology often observed in combat injured casualties who have sustained severe, high energy polytraumatic extremity injuries. Once HO has developed, prophylactic therapies are limited outside of surgical excision. Tourniquet-induced ischemia injury (IR) exacerbates trauma-mediated musculoskeletal tissue injury, inflammation, osteogenic progenitor cell development and HO formation.

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In this study, a 3D-printed photocurable resin was developed by incorporating graphene nanoplatelets functionalised with melamine to investigate the thermal, mechanical, fracture and shape memory behaviours. The objective of this work was to produce a printed functionally graded nanocomposite material that has a smart temperature-responsive structure; presents good thermal stability, strength and fracture toughness; and can demonstrate shape-changing motions, such as sequential transformations, over time. The functionalised graphene nanoplatelets were examined via thermogravimetric analysis, Fourier transform infrared spectroscopy, Raman spectroscopy and ultraviolet-visible spectroscopy.

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The lack of well-developed repair techniques limits the use of thermoplastic composites in commercial aircraft, although trends show increased adoption of composite materials. In this study, high-performance thermoplastic composites, viz., carbon fibre (CF) reinforced Polyetherketoneketone (PEKK) and Polyether ether ketone (PEEK), were subjected to low-velocity impact tests at 20 J.

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Some of the most common human systemic diseases-both benign and malignant-affect bone regulation, formation, and homeostasis (the cellular balance regulated by osteocytes, osteoblasts, and osteoclasts). This review discusses our current understanding of the molecular components and mechanisms that are responsible for homeostasis and interactions resulting in dysregulation (dysfunction due to the loss of the dynamic equilibrium of bone homeostasis). Knowledge of key pathways in bone biology can improve surgeon understanding, clinical recognition, and treatment of bone homeostasis-related diseases.

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Article Synopsis
  • Severe open lower extremity injuries require careful debridement to eliminate contaminated and non-viable tissues, while preserving any viable tissues that can be used for future reconstruction.
  • The aim of reconstruction is to restore as much functionality to the limb as possible, with the choice between salvaging the limb or opting for amputation depending on various factors like the type of injury and patient needs.
  • The article discusses strategies for preserving viable tissues as "spare parts" during debridement and how these can be utilized later as grafts to improve healing and limb function.
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Case: A 30-year-old semiprofessional football player presented with chronic bilateral quadriceps tendon ruptures. Both quadriceps tendon ruptures were unsuitable for isolated primary repair because of tendon retraction and immobility. A novel reconstruction technique using semitendinosus and gracilis tendon autografts was performed to restore both lower extremities' disrupted extensor mechanisms.

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Strains LMG 7974 and LMG 8286 represent single, novel lineages with and as nearest phylogenomic neighbours, respectively. The results of average nucleotide identity (ANI) and digital DNA-DNA hybridization (dDDH) analyses of LMG 7974, LMG 8286 and type strains of species of the genus confirmed that these strains represent novel species of the genus . The 16S rRNA gene sequences of both strains showed highest identity towards (97.

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A digital twin is a digital representation of a physical entity that is updated in real-time by transfer of data between physical and digital (virtual) entities. In this manuscript we aim to introduce a digital twin framework for robotic drilling. Initially, a generic reference model is proposed to highlight elements of the digital twin relevant to robotic drilling.

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Background: Percutaneous epiphysiodesis using transphyseal screws (PETS) is a common procedure to correct lower extremity limb-length discrepancies in the pediatric population. A potential complication of this procedure is development of tibial valgus deformity, which may occur secondary to decreased screw purchase in the thinner medial proximal tibial epiphysis. The thickness of the proximal tibial epiphysis has not yet been well quantified, which was the aim of this study.

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The use of composite materials is increasing in industry sectors such as renewable energy generation and storage, transport (including automotive, aerospace and agri-machinery) and construction. This is a result of the various advantages of composite materials over their monolithic counterparts, such as high strength-to-weight ratio, corrosion resistance, and superior fatigue performance. However, there is a lack of detailed knowledge in relation to fusion joining techniques for composite materials.

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Campylobacter fetus can cause intestinal and systemic disease in humans and are well-established veterinary and economic pathogens. We report the complete genomic sequences of two C. fetus subsp.

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Until recently, three-dimensional (3D) printing/additive manufacturing has not been used extensively to create medical devices intended for actual clinical use, primarily on patient safety and regulatory grounds. However, in recent years there have been advances in materials, printers, and experience, leading to increased clinical use. The aim of this study was to perform a structured systematic review of 3D-printed medical devices used directly in patient treatment.

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Background: Patellar tendon ruptures have a reported incidence of 0.68 per 100,000 person-years in the general population. The epidemiology of surgically treated patellar tendon ruptures in the US military has yet to be reported, which would provide opportunity for identification of risk factors for these otherwise healthy and active patients.

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Hamstring strains are the most prevalent injury sustained by field-sport athletes. Insufficiencies in the architectural characteristics of the hamstring muscles can heighten an athlete's risk of incurring a hamstring strain. To evaluate the influence of hamstring muscle architectural characteristics (i.

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