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Background: Globally, tremendous improvement has been made in Polio eradication since its inception in 1988. For the third time in a decade, Kenya has experienced a Polio outbreak along the border with Somalia. The affected areas were in Garissa County, replete with previous occurrences in 2006 and 2012. This article, give an account of series of events and activities that were used to stop the transmission within 13 weeks, an interval between the first and the last case of the 2013 outbreak.
Methods: In an attempt to stop further transmission and time bound closure of the outbreak, many activities were brought to fore: the known traditional methods, innovative approaches, improved finances and surge capacity. These assisted in case detection, implementation, and coordination of activities. The external outbreak assessments and the six-monthly technical advisory group recommendations were also employed.
Result: There were increased case detections of >=2/100,000, stool adequacy >=80%, due to enhanced surveillance, timely feedbacks from laboratory investigation and diagnosis. Sustained coverage in supplemental immunisation of > 90%, ensured that immune profile of >=3 polio vaccine doses was quickly attained to protect the targeted population, prevent further polio infection and eventual reduction of cases coming up with paralysis.
Conclusion: Overall, the outbreak was stopped within the 120 days of the first case using 14 rounds of supplemental immunisation activities.
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http://dx.doi.org/10.29245/2578-3009/2021/S2.1103 | DOI Listing |
Zhonghua Jie He He Hu Xi Za Zhi
September 2025
Neuromuscular diseases are often accompanied by various types of sleep-related breathing disorders, which can exacerbate the underlying condition and are associated with a poor prognosis. Early identification is essential, and interventions such as non-invasive ventilation, oxygen therapy, and respiratory rehabilitation should be initiated promptly to mitigate disease progression and improve outcomes. Nevertheless, the rates of missed and misdiagnosed cases remain common in clinical practice.
View Article and Find Full Text PDFPLoS One
September 2025
Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Background: Foreign-born children may face greater barriers to accessing routine immunizations in Canada or their country of birth, but provincial surveillance data on immigration status are lacking. Using our provincial immunization repository linked to administrative data, we assessed immunization coverage among immigrant and refugee children in Ontario, Canada, compared with Ontario-born children and identified factors associated with being up-to-date (UTD).
Methods: We conducted a retrospective cohort study of children entering school during the 2012/13-2014/15 school years.
J Neurol
September 2025
Department of Neurological, Neuropsychological, Morphological and Motor Sciences, University of Verona Medical School, 37134, Verona, Italy.
Despite extensive research, the pathogenesis of Post-Polio Syndrome (PPS) remains unclear. We investigated 251 participants from Northern Italy: long-term polio survivors with PPS, long-term polio survivors with stable polio, family members of both groups, subjects with neurological disorders other than poliomyelitis, and healthy controls. This study investigated whether persistent viral activity or the existence of viral reservoirs contributes to causing PPS.
View Article and Find Full Text PDFClin Infect Dis
September 2025
Department of Pediatrics, Geisel School of Medicine at Dartmouth, Dartmouth Health, Lebanon, New Hampshire, USA.
Background: Approximately 1.5 billion doses of novel oral polio vaccine type 2 (nOPV2) have been administered in response to circulating vaccine-derived poliovirus type 2 (cVDPV2) outbreaks since 2021. Although infants are eligible to receive the vaccine from birth, the induction of intestinal mucosal immunity by nOPV2 in newborns has not been directly evaluated.
View Article and Find Full Text PDFSci Rep
August 2025
Department of Mathematics and Statistics, King Faisal University, 31982, Hofuf, Saudi Arabia.
This paper presents a comprehensive study of poliomyelitis transmission dynamics using two fractional-order models that incorporate the Atangana--Baleanu derivatives in the Caputo sense (ABC). The model includes critical epidemiological features, including vaccination and a post-paralytic population class. By utilizing the Mittag-Leffler kernel, the fractional framework captures memory and hereditary properties in disease progression.
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