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http://dx.doi.org/10.1016/j.jinf.2021.04.006 | DOI Listing |
Can J Infect Dis Med Microbiol
August 2025
Department of Laboratory Medicine, Daejeon Eulji Medical Center, Eulji University, Daejeon, Republic of Korea.
This study aims to determine the molecular features and antimicrobial resistance of (Group B streptococcus, GBS) causing invasive and noninvasive infections in Korean adults. Sequence type (ST), capsular serotype, pilus island typing, and antimicrobial susceptibility were analyzed for GBS isolates obtained at a hospital laboratory that processed the primary clinical specimens collected from Korean adults between 2021 and 2024. Among the 90 isolates, Serotype VIII (34.
View Article and Find Full Text PDFCell Metab
August 2025
Section of Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA. Electronic address:
Diet and obesity contribute to insulin resistance and type 2 diabetes, in part via the gut microbiome. To explore the role of gut-derived metabolites in this process, we assessed portal/peripheral blood metabolites in mice with different risks of obesity/diabetes, challenged with a high-fat diet (HFD) + antibiotics. In diabetes/obesity-prone C57BL/6J mice, 111 metabolites were portally enriched and 74 were peripherally enriched, many of which differed in metabolic-syndrome-resistant 129S1/129S6 mice.
View Article and Find Full Text PDFBMC Infect Dis
September 2025
Department of Laboratory Medicine, West China Second University Hospital, Sichuan University, No.20, Section 3, Renmin South Road, Chengdu, Sichuan, 610041, P.R. China.
Background: Early-onset neonatal sepsis (EOS) is a critical condition primarily caused by maternal-fetal transmission of bacterial pathogens during delivery, with Escherichia coli and Group B Streptococcus being the most prevalent. However, neonatal sepsis can also involve other rare bacteria, including Corynebacterium amycolatum, which was first described in 1988 and is widely recognized as an emerging pathogen in infectious diseases.
Case Presentation: A male infant was admitted to the neonatal intensive care unit (NICU) due to premature birth and tachypnea.
Bioorg Chem
August 2025
Division of Molecular Microbiology and Immunology, CSIR-Central Drug Research Institute, Lucknow, Uttar Pradesh 226031, India; Academy of Scientific and Innovative Research (AcSIR), New Delhi, India. Electronic address:
Antimicrobial resistance is recognized as a threat to healthcare systems worldwide and consequently, discovery and development of new antimicrobials is a top priority. Natural products and their derivatives have historically been an excellent source of antimicrobials. In this context, anti-bacterial activity of synthesized natural product derivative, Rheinal, was assessed against a panel of Gram-positive and Gram-negative bacterial pathogens where it exhibited potent bactericidal activity against S.
View Article and Find Full Text PDFMicrobiol Spectr
September 2025
Division of Infectious Diseases, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
Mixed bloodstream infections (BSIs) involving and other bacterial pathogens present significant diagnostic and therapeutic challenges. The incidence of these co-infections has been increasing. However, the limited literature on this topic necessitates a deeper understanding of its epidemiological and clinical characteristics.
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