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Objective: To evaluate the surface topography and element proportion changes in clinically failed implants after different modalities in vitro debridement and to compare the cleaning effect of different method combinations.
Material And Methods: Thirty clinical failed implants were treated by different debridement methods in vitro as follows: Group 1: physiologic saline irrigation; Group 2: glycine powder air polishing; Group 3: glycine powder air polishing + ethylenediaminetetraacetic acid (EDTA); Group 4: polyetheretherketone (PEEK) tip ultrasonic scaling; and Group 5: PEEK tip ultrasonic scaling + EDTA. The relative contaminated area reduction (RCAR), visual analogue scale (VAS, the higher value means, the better cleaning effect) and surface roughness were assessed using scanning electron microscopy (SEM), stereoscopic microscopy (SM) and white light interferometry (WLI). Surface chemistry was determined by energy dispersive spectroscopy (EDS).
Results: Group 4 and Group 5 showed higher RCARs (82.90%, 82.89%), VAS scores (2.61, 2.33) and roughness reductions (-0.85 μm, -1.80 μm). Group 3 attained the highest decrease of C% (carbon, -26.67%), O% (oxygen, -13.71%) and N% (nitrogen, -5.66%), and the highest increase of Ti% (titanium, 49.67%). PEEK remnants were detected on the implant surface of Groups 4 and 5.
Conclusion: Within the limitation of the present in vitro design, PEEK tip ultrasonic scaling was more effective in eliminating visible contamination, while glycine powder air polishing combined with EDTA treatment was more conducive to expose the original surface element distribution. Both methods have their own advantages in decontamination, but none of them could reconstruct the surface as the pristine implant.
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http://dx.doi.org/10.1111/clr.13697 | DOI Listing |
ACS Omega
September 2025
Department of Horticultural Science, Texas A&M University, College Station, Texas 77843, United States.
The limited water solubility and environmental instability of natural pesticidal compounds impede their broader agricultural use. This study reports an amphiphile-assisted nanoprecipitation method to imbibe azadirachtin-rich neem seed extract (NSE) within a glycine carrier matrix, yielding a stable nanocomposite biopesticide. The formulation, prepared using polyoxyethylene sorbitan monooleate as a stabilizer and glycine as the matrix former, followed by lyophilization, exhibited a hydrodynamic diameter of ∼8 nm when redispersed in water.
View Article and Find Full Text PDFInt J Mol Sci
August 2025
Department of Oral Physiology, College of Dentistry, Dankook University, Cheonan 31116, Republic of Korea.
Constipation is a prevalent gastrointestinal disorder that significantly impairs quality of life. While pharmacological agents such as loperamide are widely used to induce constipation in experimental models, there is increasing interest in natural alternatives for alleviating intestinal dysfunction. In this study, we investigated the laxative effects of soybean powder fermented by DKU_09 in a loperamide-induced rat model of constipation.
View Article and Find Full Text PDFFront Physiol
July 2025
Department of Periodontology and Oral Mucosa, Changsha Stomatological Hospital, School of Dental Medicine, Hunan University of Chinese Medicine, Changsha, Hunan, China.
Purpose: This study aimed to systematically compare the efficacy of erythritol, glycine, and trehalose as subgingival subgingival air polishing powders in non-surgical periodontal treatment (NSPT).
Methods: Randomized controlled trials (RCTs) that met the inclusion and exclusion criteria were selected from PubMed, Embase, Web of Science, and Cochrane Library databases (up to August 2024). The sample size, treatment time, and outcome indicators including periodontal probing depth (PPD), clinical attachment level (CAL), and bleeding on probing (BOP) were extracted from the articles.
Food Res Int
October 2025
College of Grain Science and Technology, Shenyang Normal University, Shenyang 110034, PR China. Electronic address:
Qingke, a specialty cereal from the Tibetan Plateau, is known for its rich content of proteins, polyphenols, β-glucan, and other bioactive compounds. The incorporation of Qingke powder into soybean paste enhances both its flavor and nutritional profile. However, there is a need to deepen the understanding of how microbial communities and physicochemical changes contribute to the flavor and nutritional characteristics of Qingke-based fermented products.
View Article and Find Full Text PDFZhongguo Zhong Yao Za Zhi
May 2025
Beijing Key Laboratory of Research of Chinese Medicine on Prevention and Treatment for Major Diseases, Experimental Research Center, China Academy of Chinese Medical Sciences Beijing 100700, China.
Central sensitization(CS) is an important factor in inducing neuropathic pain(NPP), and the association between signal transduction protein 1(Epac1) and piezoelectric type mechanosensitive ion channel component 2(Piezo2) is a new and significant pathway for initiating CS. This study whether the central analgesic effect of Maxiong Powder is achieved through the synchronized regulation of the Epac1-Piezo2 signaling pathway in the medial habenular nucleus(MHb) and interpeduncular nucleus(IPN) of the brain. Dynamic in vivo microdialysis, combined with high-performance liquid chromatography-fluorescence detection(HPLC-RFC), behavioral assessments, immunohistochemistry, Western blot, and quantitative reverse transcription PCR, were employed in rats with partial sciatic nerve injury(SNI) to investigate the distribution and expression of Epac1 and Piezo2 proteins and genes in the MHb and IPN regions, and the changes in the extracellular levels of glutamate(Glu), aspartic acid(Asp), and glycine(Gly).
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