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http://dx.doi.org/10.1111/pace.14118 | DOI Listing |
Reumatol Clin (Engl Ed)
September 2025
Rheumatology Unit, Hospital Universitari Vall Hebron, Spain.
Background: Psoriatic arthritis (PsA) affects joints and entheses. The objective is to use ultrasound (US) to see inflammatory changes in joints and entheses in patients with active PsA starting Apremilast.
Primary Objective: 20% reduction in the US index (UIC) at 12 months.
Thyroid
September 2025
Department of Molecular Diagnostics, Department of Endocrinology, The Core Laboratory in Medical Center of Clinical Research, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
is a major cause of congenital hypothyroidism (CH) in Chinese patients, but clinical outcomes for those with biallelic mutations remain unclear. This study aimed to describe the clinical manifestations of CH due to defect. One hundred eighty-one patients with primary CH were recruited initially and were subjected to genetic screening.
View Article and Find Full Text PDFHum Reprod
September 2025
Department of Philosophy and Moral Sciences, Bioethics Institute Ghent, Ghent University, Ghent, Belgium.
Study Question: What information does an international group of professionals and egg donors consider relevant and morally necessary for prospective egg donors to provide valid informed consent?
Summary Answer: Participants considered 80% of all concrete information items (CIIs) to be relevant (e.g. all legal aspects) and 67% to be morally necessary.
Acute Crit Care
August 2025
Department of Intensive Care Unit, Maternal and Child Health Hospital of Hubei Province, Wuhan, China.
Background: To explore the value of the diaphragm thickness fraction (TF) and diaphragm mobility (DM) measured by ultrasound for predicting ventilator withdrawal success in patients with acute respiratory distress syndrome (ARDS) after cardiac surgery.
Methods: This study included 246 patients undergoing the spontaneous breathing trial. Diaphragmatic function was evaluated by ultrasound, including the diaphragm thickness at the end of calm breathing (thickness of the diaphragm at functional residual capacity [TdiFRC]) and the maximum diaphragm thickness at the end of inspiration (thickness of the diaphragm at full vital capacity [TdiFVC]); TF=(TdiFVC-TdiFRC)/TdiFRC×100%.
Cancer Causes Control
September 2025
Department of Medicine, School of Medicine, College of Health Sciences, Makerere University, P.O Box 7072, Kampala, Uganda.
Background: Most women in the low- and middle-income countries who develop cervical cancer are diagnosed at advanced stages following symptomatic presentations to healthcare professionals. This study sought to describe the symptoms experienced, symptoms' attributions, and factors associated with the perceived causes of the symptoms among a cohort of cervical cancer patients.
Methods: This was a cross-sectional study conducted at the Uganda Cancer Institute (UCI) during October 2019 to January 2020.