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Epidemiologic studies have found associations between fine particulate matter (PM) exposure and adverse health effects using exposure models that incorporate monitoring data and other relevant information. Here, we use nine PM concentration models (i.e., exposure models) that span a wide range of methods to investigate i) PM concentrations in 2011, ii) potential changes in PM concentrations between 2011 and 2028 due to on-the-books regulations, and iii) PM exposure for the U.S. population and four racial/ethnic groups. The exposure models included two geophysical chemical transport models (CTMs), two interpolation methods, a satellite-derived aerosol optical depth-based method, a Bayesian statistical regression model, and three data-rich machine learning methods. We focused on annual predictions that were regridded to 12-km resolution over the conterminous U.S., but also considered 1-km predictions in sensitivity analyses. The exposure models predicted broadly consistent PM concentrations, with relatively high concentrations on average over the eastern U.S. and greater variability in the western U.S. However, differences in national concentration distributions (median standard deviation: 1.00 μg m) and spatial distributions over urban areas were evident. Further exploration of these differences and their implications for specific applications would be valuable. PM concentrations were estimated to decrease by about 1 μg m on average due to modeled emission changes between 2011 and 2028, with decreases of more than 3 μg m in areas with relatively high 2011 concentrations that were projected to experience relatively large emission reductions. Agreement among models was closer for population-weighted than uniformly weighted averages across the domain. About 50% of the population was estimated to experience PM concentrations less than 10 μg m in 2011 and PM improvements of about 2 μg m due to modeled emission changes between 2011 and 2028. Two inequality metrics were used to characterize differences in exposure among the four racial/ethnic groups. The metrics generally yielded consistent information and suggest that the modeled emission reductions between 2011 and 2028 would reduce absolute exposure inequality on average.
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http://dx.doi.org/10.1016/j.envres.2020.110432 | DOI Listing |
JAMA Intern Med
September 2025
Department of Health Care Policy, Harvard Medical School, Boston, Massachusetts.
Importance: Hospitals have reported growing difficulty in discharging patients in a timely manner, often citing bottlenecks in postacute care. Medicare Advantage plans, now the dominant form of Medicare coverage, may contribute to these delays due to administrative and network constraints, yet national evidence is lacking.
Objective: To quantify changes in hospital length of stay for Medicare Advantage vs traditional Medicare beneficiaries.
JAMA Neurol
September 2025
Translational Neuropathology Research Laboratory, Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia.
Importance: Exposure to fine particulate matter air pollution (PM2.5) may increase risk for dementia. It is unknown whether this association is mediated by dementia-related neuropathologic change found at autopsy.
View Article and Find Full Text PDFJAMA Pediatr
September 2025
Department of Health Policy and Management, Rollins School of Public Health, Emory University, Atlanta, Georgia.
Importance: For the first time in nearly 2 decades, the US infant mortality rate has increased, coinciding with a rise in overdose-related deaths as a leading cause of pregnancy-associated mortality in some states. Prematurity and low birth weight-often linked to opioid use in pregnancy-are major contributors.
Objective: To assess the health and economic impact of perinatal opioid use disorder (OUD) treatment on maternal and postpartum health, infant health in the first year of life, and infant long-term health.
JAMA Netw Open
September 2025
Department of Social Epidemiology, Graduate School of Medicine and School of Public Health, Kyoto University, Kyoto, Japan.
Importance: Previous studies have suggested that social participation helps prevent depression among older adults. However, evidence is lacking about whether the preventive benefits vary among individuals and who would benefit most.
Objective: To examine the sociodemographic, behavioral, and health-related heterogeneity in the association between social participation and depressive symptoms among older adults and to identify the individual characteristics among older adults expected to benefit the most from social participation.
J Gerontol A Biol Sci Med Sci
September 2025
Institute of Epidemiology and Medical Biometry, Ulm University, Ulm, Germany.
Background: Ambulatory older residents in long-term care(LTC) have the highest risk of falling. However, the relationship between ambulatory activity (steps per day) and fall risk in LTC is unclear. This study examined whether baseline daily step count, functional capacity and cognitive function predicted falls in LTC residents, and whether functional capacity modified the relationship between step count and fall risk.
View Article and Find Full Text PDF