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The optical measurement algorithm for the real front and back surfaces of contact lenses from their center to periphery accurately and simultaneously is proposed. It is an algorithm that makes light incident vertically along the curved surfaces of contact lenses under the condition that the difference of curvature radii between the front and back surfaces is small enough within the NA of the optical probe. For this purpose, we adopted time-domain optical coherence tomography (OCT) with translation and rotation mechanisms. The shape, thickness distribution, and curvature radii of both surfaces were estimated with OCT signal analysis and circular approximation. The measured results were compared with the designed values and the measured data from a conventional shape measurement device. The curved shape of both surfaces and thickness were well matched with the designed values from lens center to periphery. In a curvature radius of the front surface, there was a proportional bias with a limit of agreement of -0.77 to -2.09, and the correlation coefficient was 0.57. On the back surface, there was no systematic bias, and minimal detectable change was 0.178 mm, in a range of 95% confidential interval. The proposed algorithm well visualized the real shape and optical characteristics of the contact lens with enough accuracy to the design.
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http://dx.doi.org/10.1364/AO.399190 | DOI Listing |
Electrophoresis
September 2025
School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, Guangdong Province, P. R. China.
A novel post-modification strategy was developed for rapid functionalization of monoliths through amino-yne click chemistry. This approach enabled the conjugation of activated alkynes onto amino-functionalized organic-silica hybrid monolith surfaces under mild, catalyst-free conditions. Systematic investigation of critical reaction parameters was conducted to optimize the post-modification process.
View Article and Find Full Text PDFJ Biomed Mater Res B Appl Biomater
September 2025
Contipro a.s., Czech Republic.
Drug delivery to the central nervous system (CNS) is primarily hindered by the blood-brain barrier (BBB). To address this, mucoadhesive formulations have been designed to prolong residence time at the application site. In this study, we comprehensively characterized the physicochemical and mucoadhesive properties of hyaluronic acid tyramine (HATA) photocrosslinked hydrogels using rheological methods, nanoindentation, contact angle goniometry, and advanced confocal microscopy.
View Article and Find Full Text PDFBiosens Bioelectron
August 2025
Department of Chemical Science and Technologies, University of Rome "Tor Vergata", Via Della Ricerca Scientifica, 00133, Rome, Italy; SENSE4MED, via Bitonto 139, 00133, Rome, Italy. Electronic address:
Phytic acid is a phosphorylated derivative of myo-inositol that is ubiquitous in plants and serves as the primary storage form of phosphorus. In human nutrition, phytic acid is considered an anti-nutrient because it chelates essential minerals, including calcium, iron, and zinc. This binding action reduces the bioavailability of these metals, highlighting the importance of monitoring phytic acid in food.
View Article and Find Full Text PDFJ Colloid Interface Sci
September 2025
Key Laboratory for Colloid and Interface Chemistry (Ministry of Education), Shandong University, Jinan 250100, PR China; National Engineering Research Center for Colloidal Materials, Shandong University, Jinan 250100, PR China. Electronic address:
Hypothesis: The surface free energy (γ) and solubility (δ) parameters are two important characteristic parameters describing physicochemical properties of substances, but knowledge about the characteristic parameters (γ and δ) of surfactants is still lacking. Possible relationships of the characteristic parameters of surfactants with their head group types and alkyl chain lengths as well as with the surface tension (σ) of their aqueous solutions are worth exploring.
Methods: Solid surfactants including 10 anionic and 14 cationic ones were chosen.
J Colloid Interface Sci
September 2025
State Key Laboratory of Heavy Oil Processing, China University of Petroleum (Beijing), Changping, 102249, China. Electronic address:
Carbon-based catalysts with free-standing structure are essential for rechargeable zinc-air battery as electrodes, which can avoid the side effects brought by organic binder. However, the current preparation methods still can be improved for faster preparation process and morphology control. In this study, we reported a fabrication strategy of self-standing carbon catalyst loaded with CoFe nanoparticles and carbon nanotube as air electrodes for liquid rechargeable zinc-air battery.
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