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Objective: To estimate the duration of time required following varicocelectomy to wait for the improvements of semen parameters. Therefore, we characterized the changes with the time in sperm parameters in men after varicocelectomy.
Materials And Methods: In this prospective cohort study we included consecutively observed men who underwent varicocelectomy between September 2017 and September 2018 in a referral academic hospital. Clinical data of the patients, as well as their semen parameters, were measured before surgery and at 3 and 6 months afterward.
Results: In this study, a total of 100 men with average age of 29.5 ± 6.2 years were included. Mean sperm concentration and sperm motility significantly improved by 3 (p < 0.05), but not by 6 months following varicocelectomy. The semen volume and sperm with normal morphology were the same before and after surgery (p > 0.05). There was no statistically significant difference in the improvement of semen parameters when comparing 6 months to 3 months postoperatively (p > 0.05).
Conclusions: Sperm parameters (concentration and motility) improve by 3 months after varicocelectomy without further improvements. Consequently, physicians should decide quickly after 3-month of varicocelectomy if surgery has been not helpful and then plan other therapies, like assisted reproductive technology (ART) for managing infertility in couples.
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http://dx.doi.org/10.4081/aiua.2020.3.259 | DOI Listing |
Curr Opin Urol
September 2025
Department of Urology.
Purpose Of Review: Infertility affects approximately 15% of couples, with male factors implicated in more than 50% of cases. Concerns over declining semen quality - evidenced by a more than 50% drop in sperm concentration over four decades - have triggered investigation into modifiable lifestyle and environmental factors. This review summarizes recent evidence on exposures that negatively impact male fertility.
View Article and Find Full Text PDFCureus
August 2025
Andro-Urology Unit, Institute of Kidney Diseases, Hayatabad Medical Complex, Peshawar, PAK.
Background: Varicocele is a common, correctable cause of male infertility, often associated with impaired spermatogenesis. Microsurgical subinguinal varicocelectomy is considered the gold standard for varicocele repair, with documented benefits on semen quality, particularly sperm count.
Objective: The objective of this study was to evaluate the effect of microsurgical varicocelectomy on sperm count in infertile men diagnosed with clinical varicocele.
Front Endocrinol (Lausanne)
September 2025
Department of Pharmacology, Wrocław Medical University, Wrocław, Poland.
Hypergonadotropic hypogonadism is usually caused by the impairment of the structure and function of the gonads, but there are cases caused by reduced stimulation by the follicle-stimulating hormone (FSH) as a result of abnormal variants of genes encoding the follicle-stimulating hormone or its receptor (FSHR). We present the case of an elite athlete with the c.2039A>G variant in one allele of the FSHR gene resulting in hypergonadotropic hypogonadism, low testicular volume, and reduced semen parameters, placing particular emphasis on the diagnostic process and the importance of correct diagnosis in the context of possible treatment with gonadotropins, which can significantly improve fertility, increase testosterone levels, and, in the case of athletes, obtain approval from the anti-doping organization for treatment that increases testosterone levels.
View Article and Find Full Text PDFReprod Domest Anim
September 2025
Department of Biological Sciences, State University of Santa Cruz (UESC), Ilhéus, Bahia, Brazil.
Characterising body and reproductive morphometry and their association with epididymal sperm quality can contribute to the conservation of sambar deer (Rusa unicolor). Five adult males maintained in captivity at the Getúlio Vargas Zoobotanical Park (Salvador, BA, Brazil) were captured, anaesthetised, and subjected to bilateral orchiectomy as part of a population-control strategy. Body measurements included head circumference, thoracic diameter, total length, withers height, and body weight.
View Article and Find Full Text PDFAnim Reprod Sci
September 2025
College of Animal Science and Technology, Qingdao Agricultural University, Qingdao 266109, China. Electronic address:
Due to the current limitations of boar semen cryopreservation systems, the effective restoration of sperm quality following thawing remains a significant challenge. This study investigates whether post-thaw boar sperm can uptake exogenous long-chain fatty acids (LCFAs) and utilize them for ATP generation, thereby sustaining linear motility and enhancing sperm vitality. Boar semen was diluted in extender solutions supplemented with varying concentrations of a lipid mixture (0, 0.
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