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Article Abstract
A cyclic tetrapeptide, androsamide (), was isolated from a marine actinomycete of the genus , strain CNT-189. The planar structure of was assigned by the interpretation of 1D and 2D NMR spectroscopic data. The absolute configurations of constituent amino acids of were determined by application of the Marfey's and advanced Marfey's methods. Androsamide () strongly suppressed the motility of Caco2 cells caused by epithelial-mesenchymal transition.
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