98%
921
2 minutes
20
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7546845 | PMC |
http://dx.doi.org/10.1097/CM9.0000000000001045 | DOI Listing |
Nutr Clin Pract
September 2025
Department of Clinical Nutrition, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Objective: The cachexia index (CXI) demonstrates potential as both a diagnostic tool for cachexia and a prognostic tool for survival in cancer. However, CXI's predictive value has not been verified in cervical cancer. The purpose of this study is to investigate the prognostic value of the CXI in patients with cervical cancer treated with radiotherapy.
View Article and Find Full Text PDFCureus
August 2025
Department of Urology, Graduate School of Medicine, Yamaguchi University, Ube, JPN.
Introduction Currently, treatment regimens incorporating immune checkpoint inhibitors (ICIs) are the standard of care for locally advanced or metastatic urothelial carcinoma (la/mUC). This study aimed to investigate the association between the neutrophil-to-eosinophil ratio (NER) and the occurrence of immune-related adverse events (irAEs) as well as treatment outcomes. Methods This multicenter retrospective study examined patients with la/mUC treated with ICIs between January 2017 and December 2022.
View Article and Find Full Text PDFClin Transl Gastroenterol
September 2025
Department of Internal Medicine, School of Medicine, University of Medicine and Pharmacy at Ho Cho Minh City, Vietnam.
Background: Severe acute pancreatitis (SAP) is a life-threatening condition requiring early risk stratification. While the Bedside Index for Severity in Acute Pancreatitis (BISAP) is widely used, its reliance on complex parameters limits its applicability in resource-constrained settings. This study introduces a decision tree model based on Classification and Regression Tree (CART) analysis, utilizing Neutrophil-to-Lymphocyte Ratio (NLR) and C-reactive Protein (CRP), as a simpler alternative for early SAP prediction.
View Article and Find Full Text PDFCureus
August 2025
Internal Medicine, Jaber Al-Ahmad Hospital, Al Jahra, KWT.
Heart failure (HF) remains a global health challenge with high morbidity and mortality, necessitating reliable biomarkers for risk stratification. The platelet-to-lymphocyte ratio (PLR), an emerging inflammatory marker, has shown prognostic potential in cardiovascular diseases, but its utility in HF remains inconsistently reported. This systematic review synthesizes evidence on PLR's prognostic value in HF, focusing on mortality, hospitalization, and its role in multimarker models.
View Article and Find Full Text PDFAnn Am Thorac Soc
September 2025
University of California Los Angeles David Geffen School of Medicine, Medicine, Los Angeles, California, United States.
Rationale: Inflammation is central to chronic obstructive pulmonary disease (COPD) pathogenesis but incompletely represented in COPD prognostic models. Neutrophil to lymphocyte ratio (NLR) is a readily available inflammatory biomarker.
Objectives: To explore the associations of NLR with smoking status, clinical features of COPD, and future adverse outcomes.