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Key Drosophila clock neurons remodel their axonal arborization on a daily basis. The current view is that remodelling is part of the control of clock neuron output but new data support a major role in modulating sensory inputs.
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http://dx.doi.org/10.1016/j.cub.2020.06.018 | DOI Listing |
Proc Natl Acad Sci U S A
September 2025
Department of Biology, Duke University, Durham, NC 27708.
Organisms use circadian clocks to synchronize physiological processes to anticipate the Earth's day-night cycles and regulate responses to environmental signals to gain competitive advantage. While divergent genetic clocks have been studied extensively in bacteria, fungi, plants, and animals, an ancient conserved circadian redox rhythm has been recently reported. However, its biological function and physiological outputs remain elusive.
View Article and Find Full Text PDFInt J Soc Psychiatry
September 2025
Department of Community Medicine, All India Institute of Medical Sciences, Nagpur, MH, India.
Introduction: Night Eating Syndrome (NES) is a distinct psychopathological entity variously considered as a mental health disorder, eating disorder or circadian rhythm disorder. Medical students are faced with hectic schedules, sleep interruptions and high-stakes exams as they become healthcare providers. Such social factors coupled with poor dietary practices may impact their mental health and biological clocks, leading to NES amongst this population.
View Article and Find Full Text PDFFASEB J
September 2025
Key Laboratory of Adolescent Health Assessment and Exercise Intervention, Ministry of Education, East China Normal University, Shanghai, China.
The molecular clock exhibits distinct characteristics across various tissues and can be synchronized by particular stimuli. Furthermore, there is an intricate interplay among the molecular clocks within different tissues. In this context, we present an overview of the tissue-specific molecular clock and discuss pivotal nonphotic regulators that govern the host's circadian rhythms and metabolic processes.
View Article and Find Full Text PDFPhysiol Plant
September 2025
Agriculture and Agri-Food Canada, Saskatoon Research and Development Centre, Saskatoon, Saskatchewan, Canada.
Dormancy release and germination of the seed are two separate, but continuous phases controlled by both external (e.g., light and temperature) and internal (e.
View Article and Find Full Text PDFFungal Biol
October 2025
Department of Molecular and Systems Biology, Geisel School of Medicine at Dartmouth, Hanover, NH, USA. Electronic address:
In many model organisms, the circadian system has been proposed to comprise multiple oscillators that interact to promote accuracy of the clock as well as intricacies of rhythmic outputs. In Neurospora crassa, the circadian transcriptional/translational loop comprising of the FRQ (Frequency) and WCC (White Collar Complex) proteins has been instrumental in explaining many attributes of the clock including entrainment and rhythms in development and gene expression; in addition, some non-circadian oscillations can be unmasked when the FRQ-WCC feedback loop is eliminated. These rhythms have often lost defining circadian characteristics and are potentially controlled by other oscillators, termed FRQ-less oscillators (FLOs) in Neurospora.
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