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http://dx.doi.org/10.1038/s41419-020-02817-y | DOI Listing |
Bioresour Technol
September 2025
State Key Laboratory of Food Science and Resources, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; School of Biotechnology and Key Laboratory of Industrial Biotechnology Ministry of Education, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; International Joint Laboratory on Fo
Recombinant proteins have been widely applied in the food, biomedical, and scientific fields. Prokaryotic expression systems are preferred platforms for recombinant protein production due to their rapid growth and high protein yields. Nevertheless, disparities between recombinant expression environment and native physiological conditions frequently result in protein misfolding, leading to aggregation into non-functional inclusion bodies or proteolytic degradation.
View Article and Find Full Text PDFUltrasonics
August 2025
College of Biomedical Engineering, Fudan University, Shanghai 200438, China; State Key Laboratory of Integrated Chips and Systems, Fudan University, Shanghai 200438, China; Poda Medical Technology Co., Ltd., Shanghai 200433, China. Electronic address:
Transcranial ultrasound localization microscopy (t-ULM) is faced with challenges posed by the skull, including acoustic attenuation and phase aberrations. There is a significant request for an efficient aberration correction method achieving a great balance between computational complexity and accuracy. In this study, the ray theory is first applied to in-vivo transcranial imaging to calculate the traveltime table in the inhomogeneous medium model of the imaging region.
View Article and Find Full Text PDFClin Nutr
August 2025
Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Background & Aims: Circulating proteins are integral to many biological processes and could be influenced by diet. We aimed to assess differences in the plasma proteome between people of different dietary groups, defined by degree of animal food consumption.
Methods: The UK Biobank recruited middle-aged adults (mostly 40-69 years) throughout the UK between 2006 and 2010.
Early Hum Dev
August 2025
Department of Neonatology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai 201102, China; Center for Molecular Medicine, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai 201102, China; National Health Commission (NHC) Key Lab
Objective: To synthesise current evidence on electroencephalography-based functional connectivity in preterm infants and clarify how prematurity alters early brain-network maturation.
Methods: A PRISMA-guided search (PubMed and Web of Science, inception-Mar 2025) identified 24 studies that quantified resting-state functional connectivity or graph-theory metrics in infants born <37 weeks' gestation. Study quality was rated with a six-item electroencephalography-functional connectivity checklist (reference montage, epoch length/number, artefact rejection, volume-conduction control, multiple-comparison correction).
Clin Neurophysiol
August 2025
Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK.
Objective: This study presents a comprehensive analysis of electrochemical skin conductance (ESC) values collected from over 1.9 million measurements using Withings Body Scan and Body Comp scales. It aimed at establishing descriptive values for ESC while correcting for the influence of age, sex, and circadian and seasonal variations on sudomotor function.
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