Investigating circadian patterns in electrochemical skin Conductance: A year-long retrospective analysis using home-based devices.

Objective: This study presents a comprehensive analysis of electrochemical skin conductance (ESC) values collected from over 1.9 million measurements using Withings Body Scan and Body Comp scales. It aimed at establishing descriptive values for ESC while correcting for the influence of age, sex, and circadian and seasonal variations on sudomotor function.

Validation of the French version of the Insomnia Severity Index in a population with psychiatric disorders and sleep complaints.

Insomnia disorder is a major health concern, particularly among patients with mood disorders. This study validates the translated version of the Insomnia Severity Index (ISI) in a French population with psychiatric disorders, particularly mood disorders. The ISI was completed by 260 patients with sleep complaints comorbid with psychiatric disorders, including 209 patients with mood disorders.

Bright Light Therapy in the Morning or Midday for the Treatment of Nonseasonal Depression in Bipolar Disorder (LuBi): A Dose-Escalation Phase 1/2 Randomized Double-Blind Trial.

This dose-escalation study aimed to evaluate the tolerance (hypomanic symptoms) and efficacy of bright light therapy (BLT) in depressed patients with bipolar disorder (BD) with mood stabilizers, using different schedules (duration and escalation), applied in morning or midday. Patients with BD I or II () followed a 1-week placebo phase and were randomized to morning or midday BLT with dose escalation from 7.5 to 45 minutes/d, until September 2023.

Increased sleep duration and emotional regulation in patients with major depressive episodes.

Introduction: Increased total sleep duration complaint is frequently associated with psychiatric disorders. The daytime impact of sleep disorders is directly linked to the management of emotions and behaviors. Complaints of increased total sleep duration in major depressive disorder (MDE) could be a factor in the disruption of emotional regulation, which belongs to specific, atypical and often more severe clinical pictures.

Clinical practice guidelines for switching or deprescribing hypnotic medications for chronic insomnia: Results of European neuropsychopharmacology and sleep expert's consensus group.

Introduction: Current guidelines recommend cognitive behavioural therapy for insomnia (CBT-I) as the first-line treatment for chronic insomnia. Pharmacological recommendations by European guidelines for the treatment of insomnia disorder include positive GABAergic modulators such as short and medium acting benzodiazepines and "Z-drugs" (eszopiclone, zaleplon, zolpidem, zopiclone), dual orexin receptor antagonists (DORAs; daridorexant), melatonin receptor agonists (melatonin 2 mg prolonged release - PR). Given the chronic nature of insomnia, the presence of non-responders to some treatments it is often necessary switching between various therapeutic approaches and medications.

Conditions of sleep restoration after smoking cessation: A systematic review.

Previous studies have highlighted the prevalence of disordered sleep in smokers, with subjective sleep complaints and alterations of sleep architecture, including a reduction in slow-wave sleep (SWS). These findings raise questions regarding the impact of smoking cessation and withdrawal on sleep. This review aims to assess the impact of smoking cessation on sleep by taking into account objective and subjective methods of assessment.

Exploring actigraphy as a digital phenotyping measure: A study on differentiating psychomotor agitation and retardation in depression.

Introduction: Psychomotor activity stands out as a crucial symptom in characterizing behaviors associated with depression. This study aims to explore the potential of actigraphy as a tool for digital phenotyping in characterizing symptoms of psychomotor agitation and retardation, which are clinically challenging dimensions to capture, in patients diagnosed with major depressive episode (MDE) according to DSM-5 criteria.

Methods: We compared rest-activity circadian rhythm biomarkers measured by the Motion Watch 8 actigraphy between 58 (78.

Cognitive-behavioral therapies in the management of adolescents with cannabis use disorder (CUD): A systematic review.

Introduction: Cannabis currently stands as the most prevalent illicit substance used by adolescents in France. Its use is associated with an elevated risk of developing psychiatric disorder, affecting neuro-cognitive development, or leading to psycho-social challenges in the long run. Cognitive-behavioral therapies (CBT) have emerged as a preferred approach for treating cannabis use disorders (CUD) in adults.

Study of the different sleep disturbances during the prodromal phase of depression and mania in bipolar disorders.

Background: One of the challenges in bipolar disorder (BD) lies in early detection of the illness and its recurrences, to improve prognosis. Sleep disturbances (SD) have been proposed as reliable predictive markers of conversion. While preliminary studies have explored the relationship between SD and the onset of mood episodes, the results remain heterogeneous and a few have specifically examined patients' perception of prodromal symptoms and their progression until the episode occurs.

Circadian-like patterns in electrochemical skin conductance measured from home-based devices: a retrospective study.

In this study, we investigated the potential of electrochemical skin conductance (ESC) measurements gathered from home-based devices to detect circadian-like patterns. We analyzed data from 43,284 individuals using the Withings Body Comp or Body Scan scales, which provide ESC measurements. Our results highlighted a circadian pattern of ESC values across different age groups and countries.

Effects of smoking on sleep architecture and ventilatory parameters including apneas: Results of the Tab-OSA study.

Background: The interaction between smoking and sleep seems appears to be bidirectional, but few studies evaluated the impact of smoking and its cessation on objective sleep parameters. In this context, this new study aimed to assess the impact of smoking and its cessation on sleep architecture and on ventilatory sleep parameters, particularly the presence of sleep apnea syndrome (apnea-hypopnea index (AHI)≥15). Methods: Patients hospitalized for polysomnographic sleep exploration were compared according to their smoking status: active smokers (AS), former smokers (FS), non-smokers (NoNi).

Effect of lockdown on sleep-wake rhythm and alcohol use.

The global covid-19 pandemic has imposed radical changes in daily lives. This study reflects upon sociodemographic and clinical characteristics (sleep-wake rhythm, psychiatric symptoms, and alcohol use behavior) during the full lockdown, comparing individuals who increased their alcohol use (iAU), those who maintained a stable use (sAU), and those who did not consume alcohol (AnoU). Participants were recruited via e-mails and they were required to complete an online survey that included questionnaires, during the last week of the full lockdown.