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Severely calcified lesions continue to plague endovascular interventions by negatively affecting the acute and long-term results. A new technique was developed to allow balloon crossing or to treat persistent recoil. In the direct extravascular calcium interruption arterial procedure technique, an artery forceps is percutaneously introduced to modify the plaque after conventional techniques have failed. In this initial experience, the direct extravascular calcium interruption arterial procedure technique was successful as a bailout option in patients in whom balloon crossing was impossible or recoil was untreatable even with high-pressure balloons.
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http://dx.doi.org/10.1016/j.jvscit.2020.04.007 | DOI Listing |
Quant Imaging Med Surg
August 2025
Department of Radiology, the First Hospital of China Medical University, Shenyang, China.
Background: Given the limitations of conventional imaging in accurately grading gliomas, predicting molecular subtypes, and assessing tumor proliferation and angiogenesis, there is a growing need for advanced quantitative magnetic resonance imaging (MRI) biomarkers. This study aimed to compare the diagnostic performance of histogram features of dynamic contrast enhanced (DCE) and dynamic susceptibility contrast (DSC) imaging in predicting glioma grade and genotyping, as well as to explore the association between DCE and DSC with Ki-67 and microvascular density (MVD).
Methods: Forty-six patients with gliomas were enrolled prospectively.
Front Aging Neurosci
July 2025
Neurology Department, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, China.
Parkinson's disease is a prevalent neurodegenerative disorder, where early diagnosis is essential for slowing disease progression and optimizing treatment strategies. The latest developments in artificial intelligence (AI) have introduced new opportunities for early detection. Studies have demonstrated that before obvious motor symptoms appear, PD patients exhibit a range of subtle but quantifiable motor abnormalities.
View Article and Find Full Text PDFInvest Ophthalmol Vis Sci
June 2025
Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology & Emory University, Atlanta, Georgia, United States.
Purpose: Myopia incidence is increasing globally. All-trans retinoic acid (atRA) is important in myopigenic retinoscleral signaling, motivating research on its ocular transport. However, atRA's weak autofluorescence limits its direct visualization in tissues.
View Article and Find Full Text PDFBiomaterials
January 2026
Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, 610041, China. Electronic address:
Sonodynamic therapy (SDT) offers a new, non-invasive therapeutic choice for melanoma. However, direct use of sonosensitizer like chlorin e6 (Ce6) may face problems like poor drug solubility and off-target effects. Besides, using SDT alone may be deficient to treat melanoma.
View Article and Find Full Text PDFClin Hemorheol Microcirc
April 2025
Department of Intensive Care Unit, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, China.
ObjectiveSeptic shock is a serious medical condition characterized by extreme inflammation and blood vessel permeability. Fluid resuscitation is a crucial treatment for septic shock, but the optimal approach for fluid management remains controversial. In this study, we explored how blood perfusion index (PI) monitoring can help direct fluid resuscitation therapy for septic shock.
View Article and Find Full Text PDF