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http://dx.doi.org/10.1016/j.vgie.2020.03.017 | DOI Listing |
Angew Chem Int Ed Engl
September 2025
Beijing Advanced Innovation Center for Soft Matter Science and Engineering & State Key Laboratory of Organic-Inorganic Composites, Beijing University of Chemical Technology, Beijing, 100029, P.R. China.
The donor/acceptor (D/A) interfaces in bulk heterojunction (BHJ) organic solar cells (OSCs) critically govern exciton dissociation and molecular diffusion, determining both efficiency and stability. Herein, we design a double-cable conjugated polymer, SC-1F, to insert into a physically-blended D/A system to optimize the interface. We have found that SC-1F spontaneously segregates to the interface through favorable miscibility and heterogeneous nucleation with the acceptor.
View Article and Find Full Text PDFNucleic Acids Res
September 2025
State Key Laboratory of Biocatalysis and Enzyme Engineering, School of Life Sciences, Hubei University, Hubei 430042, China.
The CRISPR/Cas12a technology has revolutionized molecular diagnostics. However, existing Cas12a systems depend on continuous target DNA activation, which limits them to single-target detection. In this study, we developed a novel topology-guided Cas12a system, the double-target responsive (DTR) system, capable of being activated by noncontiguous dual RNA/DNA targets.
View Article and Find Full Text PDFInt J Biol Macromol
September 2025
Department of Agriculture, Forestry and Bioresources, Seoul National University, Seoul, 08826, Republic of Korea; Research Institute of Agriculture and Life Science, Seoul National University, Seoul, 08826, Republic of Korea. Electronic address:
The intestinal immune microenvironment plays a crucial role in regulating systemic immune responses and is implicated in various diseases. Nevertheless, no existing model simultaneously replicates the three-dimensional (3D) immune microenvironment and the mucosal barrier. This study presents a novel mucosa-mimic model that consists of a cell-laden hydrogel matrix and a pseudo-mucus layer that emulate the intestinal lamina propria and mucosal barrier, respectively.
View Article and Find Full Text PDFOrg Lett
September 2025
State Key Laboratory of Phytochemistry and Natural Medicines, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China.
A concise enantioselective total synthesis of (+)-lucidumone, a caged polycyclic meroterpenoid with a bicyclo[2.2.2]octane skeleton, was accomplished in 10 steps (LLS) starting from commercially available 2-cyclohexen-1-one.
View Article and Find Full Text PDFJ Synchrotron Radiat
November 2025
Institute of High Energy Physics, Chinese Academy of Sciences, Beijing, China.
Synchrotron light sources are powerful platforms for cutting-edge, multidisciplinary research, with dozens currently in operation, construction or commissioning worldwide. It is widely recognized that different research areas have specific demands for source capabilities. For the majority of synchrotron facilities, delivering high-brightness, high-flux synchrotron radiation stably through high-current electron beams is the primary mode of operation.
View Article and Find Full Text PDF