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The mean stress effect in fatigue life varies by material and loading conditions. Therefore, a classical low cycle fatigue (LCF) model based on mean stress correction shows limits in asymmetric loading cases in both accuracy and applicability. In this paper, the effect of strain ratio (R) on LCF life is analyzed and a strain ratio-based model is presented for asymmetric loading cases. Two correction factors are introduced to express correlations between strain ratio and fatigue strength coefficient and between strain ratio and fatigue ductility coefficient. Verifications are conducted through four materials under different strain ratios: high-pressure tubing steel (HPTS), 2124-T851 aluminum alloy, epoxy resin and AZ61A magnesium alloy. Compared with current widely used LCF models, the proposed model shows a better life prediction accuracy and higher potential in implementation in symmetric and asymmetric loading cases for different materials. It is also found that the strain ratio-based correction is able to consider the damage of ratcheting strain that the mean stress-based models cannot.
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http://dx.doi.org/10.3390/ma13112451 | DOI Listing |
J Colloid Interface Sci
September 2025
School of Materials, Shenzhen Campus of Sun Yat-sen University, Shenzhen 518107, China. Electronic address:
Harnessing the significant buildup of lactic acid (LA) within the tumor microenvironment (TME) for metabolic manipulation presents a promising avenue for cancer treatment. Nevertheless, single-agent therapies often fail to address the complex and varying needs of TME heterogeneity, posing a substantial scientific hurdle in oncology. In this context, we employ asymmetric mesoporous silica nanoparticles (AMS NPs) as delivery vehicles, simultaneously loading them with zinc‑cobalt‑manganese ferrite nanoparticles (ZCMF NPs), lactate oxidase (LOX), and doxorubicin (DOX).
View Article and Find Full Text PDFInt J Biol Macromol
September 2025
State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Wuhan University of Technology, Wuhan, 430070, PR China. Electronic address:
Due to the poor regeneration ability of cartilage tissue, the design and fabrication of permanent hydrogel cartilage scaffolds with mechanical properties matching is still an urgent challenge. In this study, we propose an "inner swelling-outer restraint" strategy to construct Janus hydrogel for pressure-bearing cartilage replacement, which is inspired by the "Lamina-splendens" structure of cartilage. As a proof of concept, the poly(vinyl alcohol)/carboxymethyl cellulose sodium (PVA/CMCNa) layer is designed to capture more fluid by introducing negatively charged aggregates, while the macromolecular conformation of the PVA/MoS layer can be densified through wet annealing, thereby increasing the liquid permeation resistance of the PVA/CMCNa layer.
View Article and Find Full Text PDFInorg Chem
September 2025
College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University, Suzhou, Jiangsu 215123, China.
The electrochemical reduction of CO into valuable C products presents a sustainable and efficient strategy for the utilization of CO and long-term renewable energy storage. Yet, enhancing the efficiency of the electrocatalytic CO reduction reaction (eCORR) in aqueous systems remains challenging due to the difficulty in activating both CO and HO molecules. In this study, we focus on water activation generating reactive hydrogen species (*H) to boost C product selectivity.
View Article and Find Full Text PDFSmall
September 2025
Department of Chemistry, School of Chemical Sciences and Pharmacy, Central University of Rajasthan, NH-8, Bandarsindri, Ajmer, Rajasthan, 305817, India.
Designing multifunctional nanomaterials is economically and practically advantageous. Herein, this work reports a surfactant-mediated synthesis of NiTe nanoparticles (NPs) and their applications in electrocatalysis, energy storage, and sustainable green catalysis. The NiTe NPs exhibit excellent hydrogen evolution reaction (HER) activity, with a low overpotential of 309 mV versus RHE at 10 mA cm and a Tafel slope of 50 mV dec, indicating fast kinetics.
View Article and Find Full Text PDFFront Bioeng Biotechnol
August 2025
Department of Mechanical and Electro-Mechanical Engineering, TamKang University, New Taipei City, Taiwan.
Introduction: Patients with hemifacial microsomia exhibit varying degrees of mandibular asymmetry. The commercial plates used during bilateral sagittal split osteotomy (BSSO) surgery are often not tailored to individual patients and may lack sufficient fixation stability, increasing the risk of mandibular relapse. This study proposes a patient-specific plate design by collecting CT images of 30 cases of hemifacial microsomia to statistically analyze mandibular asymmetry.
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