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http://dx.doi.org/10.1007/s11606-020-05911-1 | DOI Listing |
Mol Immunol
September 2025
Cytogenetics Laboratory, Department of Zoology, Banaras Hindu University, 221005, India. Electronic address:
The innate immune response is a double-edged sword in insects, comprising the humoral and cellular mechanisms to fight and eliminate pathogens. The humoral response is achieved by the production of antimicrobial peptides, which are secreted in the hemolymph. The cellular responses are mediated by phagocytosis, encapsulation and melanization.
View Article and Find Full Text PDFTrends Cancer
September 2025
Department of Gastroenterology, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang Province, 310058, China; Institution of Gastroenterology, Zhejiang University, Hangzhou, Zhejiang Province, 310058, China. Electronic address:
Glucose restriction generally limits tumor growth. Recently, Wu et al. reported that glucose restriction inhibits primary tumors but promotes lung metastasis by forming a macrophage-dominated, natural killer (NK) cell-deficient pre-metastatic niche (PMN).
View Article and Find Full Text PDFAdv Child Dev Behav
September 2025
Department of Psychology, University of Michigan, Ann Arbor, MI, USA.
Essentialism is the intuitive belief that certain categories, such as "tiger," "boy," or "gold," have an underlying reality that goes beyond surface appearances. Childhood essentialism provides insights regarding the nature, origins, and development of human cognition. This chapter reviews the current state of the art regarding research on childhood essentialism, addressing five key issues: (1) what is essentialism and why is it important?; (2) the role of experience (including context, culture, and identity); (3) language as a uniquely powerful mode of transmission; (4) developmental origins; and (5) consequences for social issues and education.
View Article and Find Full Text PDFEgypt Heart J
September 2025
Department of Medicine, Faculty of Medicine, Tbilisi State Medical University, Tbilisi, Georgia.
Background: ST-elevation myocardial infarction (STEMI) is a major cardiac event that requires rapid reperfusion therapy. The same reperfusion mechanism that minimizes infarct size and mortality may paradoxically exacerbate further cardiac damage-a condition known as reperfusion injury. Oxidative stress, calcium excess, mitochondrial malfunction, and programmed cell death mechanisms make myocardial dysfunction worse.
View Article and Find Full Text PDFFront Oncol
August 2025
School of Medicine, South China University of Technology, Guangzhou, Guangdong, China.
Gastrointestinal malignant tumors exhibit a high incidence and mortality rate among all malignancies worldwide, making them a significant concern within the field of oncology. Targeted therapy for gastrointestinal tumors has become a hot topic in recent years, and its specific mechanism remains to be further elucidated. Secreted factors, including cytokines, chemokines, and growth factors, as components of the tumor microenvironment, play a crucial role in the progression of gastrointestinal tumors.
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