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Article Abstract
The objective of this study was to determine the association of single nucleotide polymorphisms (SNPs) in selected candidate genes with fattening performance traits in a commercial cattle herd. Fifteen SNPs in 12 candidate genes (, , , , , , , , , , , and ) were evaluated in 296 purebred Holstein-Friesian bulls using PCR-RFLP (polymerase chain reaction - restriction fragment length polymorphism). Associations between each segregating SNP and genetic merit for fattening performance were quantified using linear mixed models. Traits included in the study were fattening period, final weight, dry matter intake, feed conversion rate, and average daily weight gain. Apart from the general determination of the above-mentioned traits, each trait was evaluated based on the fattening periods between five selected target body weights (W1 100 kg, W2 200 kg, W3 300 kg, W4 400 kg, W5 450 kg). All markers with the exception of 530, , , and were associated with at least one of the traits. Furthermore, novel associations were observed for , , 3691 2834, and 3533 interactions. The results of this study confirm some previously reported associations. Moreover, novel associations have been identified, which may be incorporated into breeding programs to improve fattening performance.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852860 | PMC |
| http://dx.doi.org/10.5194/aab-62-9-2019 | DOI Listing |
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