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Background: Community-acquired pneumonia (CAP) is common within pediatrics and contributes disproportionately to morbidity and mortality. Necrotizing pneumonia is a well-documented complication of CAP. It is thought to be caused by necrosis and liquefaction of consolidated lung and can result in damage to lung parenchyma, including pneumatocele development. Management of necrotizing pneumonia with pneumatocele may include hospitalization, intensive care unit admission, and lengthy antibiotic courses. Severe cases may need invasive procedures.
Case Presentation: We present a case of severe necrotizing pneumonia requiring prolonged venovenous extracorporeal membrane oxygenation (V-V ECMO) with development of persistent pneumatoceles, requiring pneumonectomy while on ECMO support to allow for decannulation and extubation.
Conclusions: In critically ill patients with extensive unilateral necrotizing pneumonia with pneumatocele development, surgical intervention can be considered when attempts to wean ventilation have been unsuccessful. This case provides evidence that V-V ECMO and pneumonectomy is a viable salvage therapy in the most critically unwell children.
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http://dx.doi.org/10.1155/2019/2464390 | DOI Listing |
Cureus
August 2025
Infectious Diseases, Methodist University Hospital, Memphis, USA.
Mycoplasma pneumoniae (MP) is a bacterium commonly known to cause mild respiratory infections, especially in young children. Epstein-Barr virus (EBV) is a herpesvirus that causes infectious mononucleosis, typically a mild illness in younger individuals. However, in its severe form, EBV can cause pneumonia.
View Article and Find Full Text PDFLaryngoscope
September 2025
Department of Otolaryngology-Head and Neck Surgery, New York-Presbyterian/Weill Cornell Medical Center, New York, New York, USA.
We report the case of a 3-month-old infant with methicillin-resistant Staphylococcus aureus (MRSA) necrotizing fasciitis of the neck and chest complicated by bacteremia, pneumonia, and mediastinitis, which required multiple surgical debridements, including median sternotomy. The case is unsual given the patient's age and causative pathogen, and underscores the importance of early diagnosis, timely surgical intervention, and multidisciplinary collaboration to ensure survival.
View Article and Find Full Text PDFInfect Drug Resist
September 2025
Department of Infection Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong Province, People's Republic of China.
This study presents a rare case of severe acute bacterial skin and soft tissue infection (ABSSSI) following freshwater fish spike injury in a 73-year-old man. Within 24 hours of sustaining the wound, the patient developed septic shock and progressive necrotizing fasciitis. Despite early administration of broad-spectrum antibiotics and intensive care, his condition deteriorated, necessitating below-the-elbow amputation on hospital day four.
View Article and Find Full Text PDFFront Med (Lausanne)
August 2025
Department of Emergency Medicine, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Red yeast rice (RYR), a commonly used supplement with statin-like properties, is generally considered safe but may cause severe adverse effects such as rhabdomyolysis. We report a rare case of severe RYR-induced rhabdomyolysis complicated by acute kidney injury (AKI) and respiratory failure, with diaphragmatic dysfunction as a key contributing factor. A 78-year-old woman developed progressive proximal muscle weakness, dyspnea, and tea-colored urine after taking RYR (2 g/day) for 1 month.
View Article and Find Full Text PDFJ Wildl Dis
September 2025
Division of Wildlife Conservation, Alaska Dept of Fish and Game, 1300 College Road, Fairbanks, Alaska 99701, USA.
This report describes highly pathogenic avian influenza virus (HPAI) H5N1 infections in carnivores in Alaska, US between 2022 and 2024, including a black bear (Ursus americanus), a brown bear (Ursus arctos), and the first known report of HPAI in an ermine (Mustela ermina). The two bears were cubs, and the ermine was a young adult. The black bear and ermine were euthanized after demonstrating neurologic signs, including circling, blindness, ataxia, or seizures.
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