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A simple approach for constructing theranostic nanobeads is developed by using doxorubicin as a phase transfer agent to solubilize small iron oxide nanoclusters. The nanobeads can be specifically internalized into cancer cells with the guidance of an external magnetic field, resulting in good MRI and chemotherapy.
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http://dx.doi.org/10.1039/c9cc03868j | DOI Listing |
Phys Chem Chem Phys
September 2025
Masaryk University, Faculty of Science, Department of Chemistry, Kotlářská 2, Brno, 611 37, Czech Republic.
Structural and magnetic properties of ultra-small tetrahedron-shaped iron oxide nanoparticles were investigated using density functional theory. Tetrahedral and truncated tetrahedral models were considered in both non-functionalized form and with surfaces passivated by pseudo-hydrogen atoms. The focus on these two morphologies reflects their experimental relevance at this size scale and the feasibility of performing fully relaxed, atomistically resolved first-principles simulations.
View Article and Find Full Text PDFLuminescence
September 2025
Department of Physics, Saveetha Engineering College (Autonomous), Chennai, Tamilnadu, India.
The iron nickel magnesium tetra-oxide (FeNiMgO) nanocomposites (NCs) first reported in this article were synthesized using the sol-gel method. For investigation using powder X-ray diffraction (PXRD), the presence of a cubic structure is confirmed. In Raman spectroscopy, the vibrational modes are investigated.
View Article and Find Full Text PDFNat Commun
September 2025
Physikalisches Institut, Karlsruhe Institute of Technology, Karlsruhe, Germany.
Precise control of spin states and spin-spin interactions in atomic-scale magnetic structures is crucial for spin-based quantum technologies. A promising architecture is molecular spin systems, which offer chemical tunability and scalability for larger structures. An essential component, in addition to the qubits themselves, is switchable qubit-qubit interactions that can be individually addressed.
View Article and Find Full Text PDFInt J Pharm
September 2025
Faculty of Chemistry, Jagiellonian University, Gronostajowa 2, Kraków 30-387, Poland. Electronic address:
Although temozolomide (TMZ) is routinely used in the treatment of glioblastoma multiforme, it is characterized by low stability, a short half-life, and serious side effects. Therefore, a new system for the effective, targeted delivery of TMZ based on superparamagnetic iron oxide nanoparticles (SPION) has been proposed. The nanoparticles were coated with hyaluronic acid, which acted as a stabilizing shell and targeting unit capable of effectively interacting with glioblastoma cells via the CD44 receptor.
View Article and Find Full Text PDFLangmuir
September 2025
Key Laboratory of Functional Molecular Solids (Ministry of Education), College of Chemistry and Materials Science, Anhui Key Laboratory of Biomedical Materials and Chemical Measurement, Anhui Normal University, Wuhu 241000, China.
The sluggish kinetics and diffusion of lithium polysulfide (LiPS) intermediates lead to the decline in the capacity and rate of high-energy lithium-sulfur (Li-S) batteries. Integrating adsorbents and electrocatalysts into the Li-S system is an effective strategy for suppressing the polysulfide shuttle and enhancing the redox kinetics of sulfur species. The disordered structure of the electrocatalysts exhibits significantly enhanced catalytic activity.
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