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Blood transfusions in the operating room are associated with increased morbidity and mortality as well as increased cost. The technology exists for continuous noninvasive hemoglobin monitoring (SpHb), which could allow for the rapid diagnosis and treatment of acute blood loss anemia secondary to surgical bleeding. However, the accuracy of this technology has been called into question. SpHb in the operating room could reduce cost by decreasing lab draws, unnecessary transfusions, and the morbidity associated with blood transfusions. This review examines the accuracy of noninvasive hemoglobin monitoring as well as the role it may play in the operating room.
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http://dx.doi.org/10.1053/j.jvca.2019.03.044 | DOI Listing |
Perfusion
September 2025
Cardiac Surgery Department, Bristol Royal Children's Hospital, Bristol, UK.
BackgroundDuring cardiopulmonary bypass (CPB), goal-directed perfusion (GDP) seeks to match oxygen delivery to metabolic demand, but the dynamics of oxygen extraction and intraoperative oxygen demand remain poorly understood, especially in paediatric populations. Existing models rely on limited data and assume, for example, a linear relationship between log oxygen demand and temperature.MethodsWe developed GARIX (Global AutoRegressive Integrated model with eXogenous variables and an equilibrium force) to predict minute-by-minute changes in oxygen extraction ratio (OER) using high-resolution intraoperative data.
View Article and Find Full Text PDFNutr Rev
September 2025
Graduate Program in Medical Sciences: Endocrinology, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, 90035-003, Brazil.
Context: The pillars of diabetes treatment include pharmacotherapy, healthy eating, physical activity, self-monitoring, education, mental health support, and smoking cessation. Interventions based on the Transtheoretical Model of Change, which consider a patient's readiness to behavioral change, may be effective for promoting sustainable self-care. However, the impact of such interventions on diabetes management requires systematic evaluation.
View Article and Find Full Text PDFJ Am Pharm Assoc (2003)
September 2025
Department of Pharmacy, University of Rochester Medical Center, Rochester, NY.
Aims: Despite robust evidence supporting continuous glucose monitoring (CGM) use, successful utilization remains relatively low. This study aimed to determine percentage of patients with a baseline time in range (TIR) <70% who achieved TIR ≥ 70% when using CGM and identify patient variables associated with achievement and/or maintenance of TIR goal within our institution.
Materials And Methods: This was a retrospective, observational review of adult patients with diabetes using CGM for at least 6-months consecutively.
Behav Brain Res
September 2025
Faculty of Human Sciences, Waseda University, 2‑579‑15 Mikajima, Tokorozawa, Saitama, Japan. Electronic address:
Insight problem solving involves overcoming an impasse when a solution seems unreachable, often experienced as an 'Aha!' moment. In such solving, shifting from an incorrect representation imposed by constraints to a correct representation through constraint relaxation is critical. Prior research compared brain activity when constraint relaxation and representation change occurred versus when they did not occur, but neural activity before and after such changes within trials has remained underexplored.
View Article and Find Full Text PDFCurr Med Res Opin
September 2025
Department of Internal Medicine, Taksim Training and Research Hospital, Istanbul, Turkey.
Introduction: Diabetes Mellitus is a chronic disease characterised by elevated plasma glucose (PG) levels. HbA1c has been widely utilized for diabetes diagnosis. However, certain conditions restrict its use.
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