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In this paper, we propose a novel multitask learning method based on the deep convolutional network. The proposed deep network has four convolutional layers, three max-pooling layers, and two parallel fully connected layers. To adjust the deep network to multitask learning problem, we propose to learn a low-rank deep network so that the relation among different tasks can be explored. We proposed to minimize the number of independent parameter rows of one fully connected layer to explore the relations among different tasks, which is measured by the nuclear norm of the parameter of one fully connected layer, and seek a low-rank parameter matrix. Meanwhile, we also propose to regularize another fully connected layer by sparsity penalty so that the useful features learned by the lower layers can be selected. The learning problem is solved by an iterative algorithm based on gradient descent and back-propagation algorithms. The proposed algorithm is evaluated over benchmark datasets of multiple face attribute prediction, multitask natural language processing, and joint economics index predictions. The evaluation results show the advantage of the low-rank deep CNN model over multitask problems.
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http://dx.doi.org/10.1155/2019/7410701 | DOI Listing |
Elife
September 2025
Department of Biology, University of Copenhagen, Copenhagen, Denmark.
Sickness-induced sleep is a behavior conserved across species that promotes recovery from illness, yet the underlying mechanisms are poorly understood. Here, we show that interleukin-6-like cytokine signaling from the gut to brain glial cells regulates sleep. Under healthy conditions, this pathway promotes wakefulness.
View Article and Find Full Text PDFEvol Anthropol
September 2025
Department of Anthropology and Center for the Advanced Study of Human Paleobiology, The George Washington University, Washington, USA.
Language is central to the cognitive and sociocultural traits that distinguish humans, yet the evolutionary emergence of this capacity is far from fully understood. This review explores how the study of the brains of language-trained apes (LTAs) offers a unique and valuable opportunity to tease apart the relative contribution of evolved species differences, behavior, and environment in the emergence of complex communication abilities. For example, when raised in sociolinguistically rich and interactive environments, LTAs show communicative competencies that parallel aspects of early human language acquisition and exhibit altered neuroanatomy, including increased connectivity and laterization in regions associated with language.
View Article and Find Full Text PDFIEEE J Biomed Health Inform
September 2025
Drug-target interaction (DTI) identification is of great significance in drug development in various areas, such as drug repositioning and potential drug side effects. Although a great variety of computational methods have been proposed for DTI prediction, it is still a challenge in the face of sparsely correlated drugs or targets. To address the impact of data sparsity on the model, we propose a multi-view neighborhood-enhanced graph contrastive learning approach (MneGCL), which is based on graph clustering according to the adjacency relationship in various similarity networks between drugs or targets, to fully exploit the information of drugs and targets with few corrections.
View Article and Find Full Text PDFIEEE Trans Neural Netw Learn Syst
September 2025
This article proposes a novel model-based planning framework for freeway ramp metering (RM), denoted as Koopman-driven linearized model-based offline planning (KLMOP). This framework integrates the model predictive control (MPC) and offline reinforcement learning (RL) under assumptions of a linear Markov decision process (MDP) with the Koopman operator. KLMOP introduces a fully linearized control framework by learning and modeling the dynamics, reward function, and value function in a latent space through a Koopman-based latent dynamical model (KLDM) and a pessimistic value iteration (PEVI) algorithm.
View Article and Find Full Text PDFJ Adult Dev
November 2024
Institute of Child Development, University of Minnesota, Minneapolis, MN, USA.
The beneficial impacts of civic participation on health are reported for adolescents and older adults. Still, civic participation is underrecognized in its potential to promote a wide range of well-being. This study aimed to investigate the relationship between civic participation in early adulthood and midlife well-being for a 1980 birth sample of minority youth who were economically disadvantaged and explore education as a mediator of such associations.
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