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Background: Sparganosis mansoni is a parasitic disease caused by infection with the larvae of Spirometra spp. tapeworms. Its clinical manifestations and severity depend on the migration and the location of the parasites. The proportion of cerebral sparganosis in all Spirometra mansoni infections is 13.5% in Thailand and 12.4% in China. In the clinical setting, cerebral sparganosis is often misdiagnosed due to atypical characteristics, irregular intracranial location, and atypical epidemiology.
Case Presentation: The patient in the case study suffered from an acute paroxysmal attack of lateral numbness, accompanied with focal epilepsy. He was admitted to the neurology department as a stroke patient but was later diagnosed with cerebral sparganosis mansoni following lab and radiology investigations. He was fully recovered and free of Spirometra mansoni one year after initial consultation following several courses of oral praziquantel. The current report focuses on the diagnosis, treatment and follow up of this patient.
Conclusions: A case of cerebral sparganosis mansoni with a stroke-like onsetsuggests that in the clinical diagnosis, neurologists should pay attention to brain lesions and look out for the possibility of neuroparasitic infections when dealing with patients with stroke-like onset accompanied by epilepsy. Detections of relevant antibodies in blood and cerebrospinal fluid may be necessary. The combination of the epidemiological history, clinical manifestations, detection of parasite antibody, head radiology, pathological biopsy, and identification of parasites will help us in diagnosis and differential diagnosis.
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http://dx.doi.org/10.1186/s12883-019-1335-1 | DOI Listing |
JAMA Neurol
September 2025
Department of Neurosurgery, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Surg Neurol Int
May 2025
Department of Neurology, Bumrungrad International Hospital, Bangkok, Thailand.
Background: Central nervous system (CNS) sparganosis is an exceptionally rare parasitic infection caused by the larvae of species. Its migratory nature and nonspecific clinical presentation often lead to misdiagnosis, posing significant diagnostic and therapeutic challenges. While CNS involvement typically affects either the brain or spinal cord, disseminated cases involving both regions are exceedingly rare.
View Article and Find Full Text PDFActa Epileptol
May 2024
Department of Neurosurgery, Affiliated Hospital of Southwest Medical University, Luzhou Sichuan, 646000, China.
Background: Cerebral sparganosis represents the most severe manifestation of sparganosis, with a relatively low global incidence. For cases of secondary epileptic seizures caused by sparganosis infection in the functional areas of the brain, what advanced neurosurgical techniques should be employed to precisely identify and excise the epileptic lesions in the deep functional areas of the brain, aiming to achieve maximal removal while minimising the risk of neurological deficits? This remains a current challenge for epilepsy surgeons.
Case Presentation: A 24-year-old Chinese male was admitted to our hospital, presenting with a history of left limb twitching persisting for over a year.
Neurology
January 2025
From the Department of Neurosurgery (H.R.P.), Soonchunhyang University Seoul Hospital, Seoul; Department of Neurosurgery (S.H.P.), Cancer Research Institute, Hypoxia Ischemia Disease Institute, Seoul National University, Seoul; and Advanced Institutes of Convergence Technology (S.H.P.), Seoul Nation
Narra J
August 2024
Department of Parasitology and Mycology, Faculty of Medicine, Universitas Sebelas Maret, Surakarta, Indonesia.