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http://dx.doi.org/10.18632/oncotarget.26829 | DOI Listing |
Int J Gen Med
August 2025
Prenatal Diagnosis Center, Department of Obstetrics and Gynecology, Women and Children's Hospital, School of Medicine, Xiamen University, Xiamen, Fujian, 361000, People's Republic of China.
Purpose: To evaluate diagnostic value of prenatal ultrasound in classifying fetal congenital heart disease (CHD) and to verify its diagnostic accuracy by comparing its results with postnatal pathological findings.
Methods: This retrospective study analyzed 372 pregnant women with fetal CHD, detected by ultrasound, who underwent interventional prenatal diagnosis. Prenatal CHD cases were classified at three levels.
Proc Natl Acad Sci U S A
September 2025
Jet Propulsion Laboratory, California Institute of Technology, Pasadena, CA 91109.
An explosion of recent research uses remote imaging spectroscopy from aircraft and spacecraft to detect and quantify methane point source emissions. These instruments first map the methane enhancement field and then combine this information with the effective wind speed to estimate the source emission rate. This wind speed is typically the largest uncertainty in derived emission rates.
View Article and Find Full Text PDFSci Rep
August 2025
Department of Psychiatry and Neuropsychology, Mental Health and Neuroscience Research Institute, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands.
Experimental autoimmune myasthenia gravis (EAMG) is an active-immunization model that was first discovered by coincidence when rabbits injected with purified acetylcholine receptor for neuromuscular junction physiology studies, suddenly developed muscle weakness. In mice, this model typically involves bilateral subcutaneous injections of purified torpedo acetylcholine receptor (tAChR) in the hind footpads and the scapular regions, followed by one or two booster immunizations in the thighs and over the scapulas. However, footpad injections can cause severe discomfort and progressive debilitation.
View Article and Find Full Text PDFNat Commun
August 2025
Howard Hughes Medical Institute, Salk Institute for Biological Studies, La Jolla, CA, USA.
Light and temperature variations are inescapable in nature. These signals provide daily and seasonal information, guiding life history determinations across many taxa. Here we show that signals from the PHOTOTROPIN2 (PHOT2) blue photoreceptor combine with low temperature information to control flowering.
View Article and Find Full Text PDFFront Microbiol
August 2025
Zoonoses Laboratory and Key Laboratory of Veterinary Pathobiology and Disease Control, College of Veterinary Medicine, Anhui Agricultural University, Hefei, China.
Duck adenovirus type-3 (DAdV-3) infections have severe effects on duck health, and rapid detection methods are crucial to reduce the morbidity and mortality associated with this pathogen in clinical practice. In this study, we established, optimized, and validated a novel recombinase polymerase amplification (RPA)-lateral flow dipstick (LFD) assay for the detection of DAdV-3. Next, we established a clinical infection model based on the pathogenicity of the DAdV-3 strain and tested the effectiveness of the RPA-LFD assay in controlling an outbreak of DAdV-3 infection.
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