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A single-shot characterization of the temporal contrast of a petawatt laser pulse with a high dynamic-range, is important not only for improving conditions of the petawatt laser facility itself, but also for various high-intensity laser physics experiments, which is still a difficult problem. In this study, a new idea for improving the dynamic-range of a single-shot temporal contrast measurement using novel temporal contrast reduction techniques is proposed. The proof-of-principle experiments applying single stage of pulse stretching, anti-saturated absorption, or optical Kerr effect successfully reduce the temporal contrast by approximately one order of magnitude. Combining with the SRSI-ETE method, its dynamic-range characterization capability is improved by approximately one order of magnitude to approximately 10. It is expected that a higher dynamic-range temporal contrast can be characterized by using cascaded temporal contrast reduction processes. The proposed techniques can also be used in the delay-scanning temporal contrast measurement to improve its dynamic range.
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http://dx.doi.org/10.1364/OE.27.010586 | DOI Listing |
Mol Pharm
September 2025
Department of Nuclear Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Tissue factor (TF) has emerged as a promising target for the diagnosis and treatment of hepatocellular carcinoma (HCC). However, there is limited data available on TF-related PET imaging for longitudinal monitoring of the pathophysiological changes during HCC formation. Herein, we aimed to explore the TF-expression feature and compare a novel TF-targeted PET probe with F-FDG through longitudinal imaging in diethylnitrosamine (DEN)-induced rat HCC.
View Article and Find Full Text PDFPLoS One
September 2025
FAMERP- Faculty of Medicine of São José do Rio Preto, Brazil.
Background: Interprofessional Education (IPE) is widely recognized as essential for fostering collaborative healthcare practices and improving patient outcomes. Despite its acknowledged importance, there remains a notable scarcity of longitudinal research assessing medical students' readiness for IPE across distinct educational stages, particularly within diverse global contexts like Brazil.
Aim: This study sought to address this gap by longitudinally mapping and analyzing the evolution of medical students' readiness for interprofessional learning throughout their academic training at a Brazilian university.
IEEE Trans Neural Netw Learn Syst
September 2025
Temporal modeling plays an important role in the effective adaption of the powerful pretrained text-image foundation model into text-video retrieval. However, existing methods often rely on additional heavy trainable modules, such as transformer or BiLSTM, which are inefficient. In contrast, we avoid introducing such heavy components by leveraging frozen foundation models.
View Article and Find Full Text PDFMed Vet Entomol
September 2025
Laboratorio de Inmunología, Centro de Investigaciones Regionales "Dr. Hideyo Noguchi", Universidad Autónoma de Yucatán, Mérida, México.
The study of population dynamics in a vertical forest gradient provides basic information on the aspects of insect vector natural history that influence the rate of pathogen transmission. In Mexico, these studies are remarkably limited for sand flies recognised as Leishmania vectors. This study analyses the temporal dynamics of sand fly species (Diptera: Psychodidae) along vertical strata of a tropical dry forest in Yucatán, Mexico, an area previously identified as a transmission hotspot for Leishmania mexicana.
View Article and Find Full Text PDFIsotopes Environ Health Stud
September 2025
School of Architecture and Environment, University of the West of England, Bristol, UK.
The natural tracers δO and δH are essential for tracing hydrological processes by identifying water sources, tracking evaporation loss and floodwater dynamics to enhance water management and flood mitigation strategies. This study employed this approach in the ephemeral, endorheic Cuvelai-Etosha Basin (CEB), spanning northern Namibia and southern Angola, to determine its viability in capturing spatial and temporal hydrological patterns, their timing and interactions during a medium flood condition (2017), and contrasted with a drought year (2014). During the 2017 wet season 219 grab surface water samples were collected from ephemeral waterbodies in four sampling campaigns (February, March, April and May) in addition to a single campaign in May 2014 (63 samples).
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