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The aim of this study was to analyze the spatial distribution of excess weight in Brazil and its correlation with household food insecurity, purchase of foods by type of processing, and Human Development Index (HDI). An ecological study was undertaken using data from three surveys conducted by the Brazilian Institute of Geography and Statistics. Spatial analysis techniques were used to perform univariate and bivariate analysis. The prevalence of excess weight was 34.2% (CI 95% 33.8-34.6%). Excess weight showed a moderate and significant spatial autocorrelation (0.581; p = 0.01), with higher prevalence in states in the South, Southeast and Center-West regions. A positive moderate spatial correlation was shown between the prevalence of excess weight and HDI (0.605; p < 0.05) and purchase of ultra-processed foods (0.559; p < 0.05), while a negative moderate spatial correlation was observed between prevalence of excess weight and household food insecurity (-0.561; p < 0.05). It can be concluded that there is an unequal distribution of excess weight across Brazil. The highest prevalence rates were found in states in the Southeast, South, and Center-West regions, associated with higher HDI values and higher ultra-processed food purchases as a proportion of overall household food purchases.
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http://dx.doi.org/10.1590/1413-81232018243.35182016 | DOI Listing |
Front Neurosci
August 2025
Beijing Life Science Academy, Beijing, China.
Hypocretin, also known as orexin, is a hypothalamic neuropeptide that regulates essential physiological processes including arousal, energy metabolism, feeding behavior, and emotional states. Through widespread projections and two G-protein-coupled receptors-HCRT-1R and HCRT-2R-the hypocretin system exerts diverse modulatory effects across the central nervous system. The role of hypocretin in maintaining wakefulness is well established, particularly in narcolepsy type 1 (NT1), where loss of hypocretin neurons leads to excessive daytime sleepiness and cataplexy.
View Article and Find Full Text PDFCase Reports Plast Surg Hand Surg
September 2025
Plastic Surgery Unit, University Hospital Trust of Sassari, Sassari, Italy.
Reconstruction of the calcaneal region presents unique challenges due to its complex anatomy and critical weight-bearing function. This retrospective study aims to report our experience in cases of calcaneal defects repaired with various free flap types, and to evaluate the long-term outcomes of the reconstructions. We retrospectively reviewed 25 patients who underwent microsurgical free flap reconstruction for calcaneal defects between January 1997 and March 2022.
View Article and Find Full Text PDFVet World
July 2025
Department of Anatomy, Faculty of Veterinary Medicine, Khon Kaen University, 123 Moo 16 Mittraphap Rd., Nai-Muang, Muang, Khon Kaen, 40002, Thailand.
Background And Aim: Primiparous sows are particularly vulnerable to prolonged weaning-to-service interval (WSI), which negatively impacts reproductive efficiency and farm profitability. This study aimed to identify critical risk factors associated with prolonged WSI (>6 days) in first-parity Landrace × Yorkshire sows raised under tropical conditions.
Materials And Methods: A retrospective cohort analysis was performed using production records from 3,222 sows on a commercial farm in Central Vietnam.
Medicine (Baltimore)
September 2025
Aerospace Center Hospital, Beijing, China.
This study examined gender-specific factors affecting multiple chronic disease burdens in Chinese adults over 45 years. This study was a prospective cohort study based on the China Health and Retirement Tracking Survey (CHARLS). A total of 6509 middle-aged and elderly people aged ≥ 45 years with 14 types of chronic diseases were included.
View Article and Find Full Text PDFMedicine (Baltimore)
September 2025
Department of Histology and Embryology, Faculty of Medicine, Dicle University, Diyarbakir, Turkey.
Excessive gestational weight gain (GWG) is associated with various adverse pregnancy outcomes, including disruption of placental function and fetal development. Iron transport through the placenta is crucial for fetal growth, and transferrin receptor 2 (TfR2) plays a key role in iron homeostasis. However, the effect of excessive GWG on placental TfR2 expression and neonatal iron parameters remains unclear.
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