Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
The limits of frequency resolution in nano-NMR experiments have been discussed extensively in recent years. It is believed that there is a crucial difference between the ability to resolve a few frequencies and the precision of estimating a single one. Whereas the efficiency of single frequency estimation gradually increases with the square root of the number of measurements, the ability to resolve two frequencies is limited by the specific timescale of the signal and cannot be compensated for by extra measurements. Here we show theoretically and demonstrate experimentally that the relationship between these quantities is more subtle and both are only limited by the Cramér-Rao bound of a single frequency estimation.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1103/PhysRevLett.122.060503 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Use of artificial intelligence for classification of fractures around the elbow in adults according to the 2018 AO/OTA classification system.
BMC Musculoskelet Disord
September 2025
Department of Clinical Sciences at Danderyds Hospital, Department of Orthopedic Surgery, Karolinska Institutet, Stockholm, 182 88, Sweden.
Background: This study evaluates the accuracy of an Artificial Intelligence (AI) system, specifically a convolutional neural network (CNN), in classifying elbow fractures using the detailed 2018 AO/OTA fracture classification system.
Methods: A retrospective analysis of 5,367 radiograph exams visualizing the elbow from adult patients (2002-2016) was conducted using a deep neural network. Radiographs were manually categorized according to the 2018 AO/OTA system by orthopedic surgeons.
Competition between tool and hand motion impairs movement planning in limb apraxia.
J Neurosci
September 2025
Jefferson Moss Rehabilitation Research Institute, Thomas Jefferson University, Elkins Park, PA 19027.
Tool use is a complex motor planning problem. Prior research suggests that planning to use tools involves resolving competition between different tool-related action representations. We therefore reasoned that competition may also be exacerbated with tools for which the motions of the tool and the hand are incongruent (e.
View Article and Find Full Text PDFDistinct Roles of Alpha and Theta Oscillations in Information-Seeking in Cognitive Control.
J Neurophysiol
September 2025
Cognitive Neurophysiology, Department of Child and Adolescent Psychiatry, Faculty of Medicine, TU Dresden, Schubertstrasse 42, 01307 Dresden, Germany.
Cognitive control - the ability to regulate information processing in line with current goals - is essential for cognitive functioning. We examined whether uncertainty in cognitive control demands leads to higher processing of cues that reduce uncertainty. Participants completed a Go/NoGo task with two NoGo:Go ratios (4:5 and 1:6).
View Article and Find Full Text PDFUnlabelled: Passive Acoustic Mapping (PAM) is rapidly emerging as a ubiquitous tool for real-time localization and monitoring of therapeutic ultrasound treatments involving cavitation in the context of safety or efficacy. The ability of PAM to spatially quantify and resolve cavitation activity offers a unique opportunity to correlate the energy of cavitation phenomena with locally observed bioeffects.
Objective: We aim to develop methods of measuring and reporting spatio-temporally varying cavitation energies that are energy-preserving, device-independent, and adequately normalized to the volume of tissue being affected by the reported cavitation activity.
A genetically encoded nanobody sensor reveals conformational diversity in β-arrestins orchestrated by distinct seven transmembrane receptors.
Proc Natl Acad Sci U S A
September 2025
Department of Biological Sciences and Bioengineering, Indian Institute of Technology, Kanpur 208016, India.
Agonist-induced interaction of G protein-coupled receptors (GPCRs) with β-arrestins (βarrs) is a critical mechanism that regulates the spatiotemporal pattern of receptor localization and signaling. While the underlying mechanism governing GPCR-βarr interaction is primarily conserved and involves receptor activation and phosphorylation, there are several examples of receptor-specific fine-tuning of βarr-mediated functional outcomes. Considering the key contribution of conformational plasticity of βarrs in driving receptor-specific functional responses, it is important to develop novel sensors capable of reporting distinct βarr conformations in cellular context.
View Article and Find Full Text PDF