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Fontan surgery and its modifications have improved survival in various forms of univentricular hearts. A regular atrial rhythm with atrioventricular synchrony is one of the most important prerequisite for the long-term effective functioning of this preload dependent circulation. A significant proportion of these survivors need various forms of pacing for bradyarrhythmias, often due to sinus nodal dysfunction and sometimes due to atrioventricular nodal block. The diversion of the venous flows away from the cardiac chambers following this surgery takes away the simpler endocardial pacing options through the superior vena cava. The added risks of thromboembolism associated with endocardial leads in systemic ventricles have made epicardial pacing as the procedure of choice. However challenges in epicardial pacing include surgical adhesions, increased pacing thresholds leading to early battery depletion and frequent lead fractures. When epicardial pacing fails, endocardial lead placement is equally challenging due to lack of access to the cardiac chambers in Fontan circulation. This review discusses the univentricular heart morphologies that may warrant pacing, issues about epicardial pacing, different techniques for endocardial pacing in patients with disconnected superior vena cava, pacing in different modifications of Fontan surgeries, issues of systemic thromboembolism with endocardial leads, atrioventricular valve regurgitation attributed to pacing leads and device infections. In a vast majority of patients following Glenn shunt and Senning surgery, an epicardial pacing and lead replacement is always feasible though technically very difficult. This article highlights the different options of transatrial and transventricular endocardial pacing.
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http://dx.doi.org/10.1016/j.ipej.2018.11.013 | DOI Listing |
Eur Heart J Case Rep
September 2025
Arrhythmia Unit, Department of Cardiology, Hospital Juan Ramon Jimenez, Ronda Norte S/N, Huelva 21005, Spain.
Background: Becker muscular dystrophy (BMD) is frequently associated with cardiac involvement. The underlying pathoanatomical substrate includes replacement of cardiomyocytes by fibrous tissue, leading to extensive myocardial fibrosis of the posterolateral wall of the left ventricular (LV) epicardium. Cardiac arrhythmias, including ventricular tachycardia (VT), are common in this condition, particularly when LV ejection fraction (LVEF) declines.
View Article and Find Full Text PDFHeart Rhythm
August 2025
Heart Rhythm Management Centre, Postgraduate Program in Cardiac Electrophysiology and Pacing, Universitair Ziekenhuis Brussel - Vrije Universiteit Brussel, European Reference Networks Guard-Heart, Brussels 1090, Belgium.
Background: Brugada syndrome (BrS) is a cardiac channelopathy predisposing individuals to malignant ventricular arrhythmias (VA) and sudden cardiac death (SCD). Substrate modification with catheter ablation (CA) has emerged as an interesting option to prevent recurrence of VA.
Objective: This systematic review and meta-analysis aimed to assess the efficacy and safety of CA in patients with high-risk symptomatic BrS.
J Cardiovasc Dev Dis
August 2025
Department of Cardiology, S. Chiara Hospital, APSS PA of Trento, 38122 Trento, Italy.
Atrial fibrillation (AF), the most prevalent sustained cardiac arrhythmia, poses a significant burden on global morbidity and healthcare expenditure. Although endocardial catheter ablation and surgical ablation are established therapeutic strategies, each exhibits inherent limitations in achieving comprehensive substrate modification. Hybrid ablation therapy, integrating both endocardial and epicardial approaches, aims to overcome these limitations by enabling the more extensive and transmural targeting of arrhythmogenic foci and the complex atrial substrate.
View Article and Find Full Text PDFJ Physiol
August 2025
Scientific Computing and Imaging Institute, University of Utah, Salt Lake City, Utah, USA.
Predictive models and computational simulations of cardiac electrophysiology depend on precise anatomical representations, including the local myocardial fibre structure. However, obtaining patient-specific fibre information is challenging. In addition, the influence of physiological variability in fibre orientation on cardiac activation simulations is poorly understood.
View Article and Find Full Text PDFVasc Health Risk Manag
August 2025
Department of Cardiology, MercyOne Iowa Heart Center, Des Moines, IA, USA.
Background: Coronary artery bypass grafting (CABG) is frequently associated with postoperative arrhythmias, often necessitating temporary cardiac pacing (TCP). The routine placement of temporary epicardial pacing wires (PWs) remains controversial due to potential complications. This study aimed to identify predictors for TCP after isolated CABG to guide selective PW use and improve perioperative outcomes.
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