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Exercise capacity has been reported to be lower in children with Juvenile Idiopathic Arthritis (JIA). Therefore, the aim was to investigate the effects of an 8-week water-based exercise program on exercise capacity in children with JIA. Forty-two children with JIA were divided into two groups as: exercise group [n = 21, water-running, moderate-intensity exercise (60-70%), two times/week], and control group (n = 21, no additional treatment other than the prescribed medication). All children were assessed at baseline and post-intervention in terms of physical and disease-related characteristics, pain at rest and in activity (visual analog scale), range of motion (Escola Paulista de Medicina Range of Motion Scale), aerobic exercise capacity (cycle ergometer), and anaerobic exercise capacity (Wingate Test). Anaerobic exercise capacity was found to be improved in the exercise group [baseline: 5.54 W/kg (IQR 25/75: 4.07/6.88 W/kg) vs. post-intervention: 6.0 W/kg (IQR 25/75: 4.8/7.4 W/kg), p = 0.002], while no improvements were observed in the control group [baseline: 5.29 W/kg (IQR 25/75: 4.75/5.85 W/kg) vs. post-intervention: 5.5 watts/kg (IQR 25/75: 5.0/6.1 W/kg), p = 0.076]. The amount of the changes related to anaerobic exercise capacity were higher in the exercise group [exercise group: 0.6 W/kg (IQR 25/75: 0.3/1.3 W/kg) vs. control group: 0.2 W/kg (IQR 25/75: - 0.1/0.5 W/kg), p = 0.024]. No changes were detected related to aerobic exercise capacity in any of the groups (p > 0.05). An 8-week water-running program might be beneficial to improve anaerobic exercise capacity, but it is not enough to improve the aerobic exercise capacity in children with JIA.
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http://dx.doi.org/10.1007/s00296-018-4209-8 | DOI Listing |
Monaldi Arch Chest Dis
September 2025
Department of Chest Disease, Istanbul Faculty of Medicine, Istanbul University.
Assessment of exercise capacity is useful in monitoring patients and planning a rehabilitation program for subjects with pulmonary hypertension (PH). No study has investigated the relationship of different field tests, except for the six-minute walk test (6MWT), with balance, activities of daily living (ADL), and quality of life (QoL) in subjects with PH. This study aimed to investigate the relationship of different field tests with balance, ADL, and QoL in subjects with PH.
View Article and Find Full Text PDFAnn Afr Med
September 2025
Department of Pediatrics, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India.
Background And Aims: Hypothyroid patients often complain of shortness of breath, fatigue, and exercise intolerance. Both inspiratory and expiratory muscles' weakness is present, and the impairment of pulmonary function may be initiated at the subclinical stage of hypothyroidism. Hence, this study aimed to assess the pulmonary function tests (PFTs) in hypothyroid patients.
View Article and Find Full Text PDFAm J Physiol Heart Circ Physiol
September 2025
Department of Kinesiology, University of Virginia, Charlottesville, VA, USA.
Nitric oxide (NO) is essential for cardiovascular health and is purported as an ergogenic aid. Endothelial dysfunction and reduced endogenous NO production are hallmarks of heart failure (HF), which may contribute to impaired exercise capacity. Oral inorganic nitrate supplementation offers an exogenous route to increase bioavailable NO via reduction of nitrate by oral commensal bacteria.
View Article and Find Full Text PDFFront Sports Act Living
August 2025
Department of Physical Education, Tianjin University of Sport, Tianjin, China.
Background: Repeated-sprint training in hypoxia (RSH) has emerged as a novel strategy to optimize repeated-sprint ability (RSA), aerobic capacity, and anaerobic performance in athletes. Although numerous studies have explored its efficacy compared with repeated-sprint training in normoxia (RSN), inconsistencies remain regarding overall benefits and modulating factors.
Objectives: This study aimed to quantify the overall effect of RSH vs.
Anal Chim Acta
November 2025
State Key Laboratory of Digital Medical Engineering, School of Biological Science and Medical Engineering, Southeast University, Nanjing, 210096, China. Electronic address:
Background: During intense exercise, anaerobic metabolism predominantly produces energy in the body, resulting in lactic acid (LA) accumulation, which contributes to muscle fatigue and soreness and may also impair neurological and cardiovascular functions. In endurance sports, the lactate threshold (LT) is a key indicator of an athlete's capacity to clear and utilize LA, directly influencing athletic performance and endurance. Therefore, LA detection is crucial for assessing the physical condition of both athletes and the general population, as well as for optimizing training programs.
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