98%
921
2 minutes
20
Assessment of exercise capacity is useful in monitoring patients and planning a rehabilitation program for subjects with pulmonary hypertension (PH). No study has investigated the relationship of different field tests, except for the six-minute walk test (6MWT), with balance, activities of daily living (ADL), and quality of life (QoL) in subjects with PH. This study aimed to investigate the relationship of different field tests with balance, ADL, and QoL in subjects with PH. This study was a prospective cross-sectional study. A total of 27 subjects who were diagnosed as having PH were included in the study. Field tests were the 6MWT, the Incremental Shuttle Walk Test (ISWT), and the Endurance Shuttle Walk Test (ESWT). Balance assessment was performed using the Timed Up and Go Test (TUG). ADL was evaluated using the London Chest Activities of Daily Living Scale, and QoL was evaluated using emPHasis-10. TUG was the significant predictor of 6MWD and ISWT walking distance (ß=-0.590, p=0.001, ß=-0.600, p=0.001). The emPHasis-10 score significantly predicted ESWT time (ß=-0.667, p<0.001). Submaximal and maximal exercise capacity were related to balance in subjects with PH, and lower endurance capacity was related to decreased QoL. This study suggests that submaximal and maximal exercise capacity were related to dynamic balance in subjects with PH, and lower endurance capacity was related to decreased QoL. ISWT can be considered a safe and practical tool to assess maximum exercise capacity.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.4081/monaldi.2025.3308 | DOI Listing |
Arch Cardiovasc Dis
September 2025
CIC INSERM 1410, 97410 Saint-Pierre, France; Department of Cardiology, La Réunion University Hospital, 97400 Saint-Denis, France. Electronic address:
Background: Artificial intelligence has emerged as a promising tool to optimize patient care in the field of cardiovascular medicine. However, data on its adoption and utilization by healthcare professionals are scarce.
Aim: To explore the factors that support or hinder the adoption of artificial intelligence in cardiology in France.
Med Eng Phys
October 2025
Mechanical Engineering Department KVGIT Jaipur, Rajasthan, India.
Triply periodic minimal surfaces have garnered significant interest in the field of biomaterial scaffolds due to their unique structural properties, including a high surface-to-volume (S/V) ratio, tunable permeability, and the potential for enhanced biocompatibility. Bone scaffolds necessitate specific features to effectively support tissue regeneration. This study examines the permeability and active cell proliferation area of advanced Triply Periodic Minimal Surface (TPMS) lattice structures, focusing on a novel lattice design.
View Article and Find Full Text PDFProc Biol Sci
September 2025
Department of Wildlife, Fish and Environmental Studies, Swedish University of Agricultural Sciences, 901 83 Umeå, Västerbotten County, Sweden.
Pharmaceutical contaminants reaching natural aquatic ecosystems can affect fish behaviour, modifying activity patterns, foraging behaviour and antipredator responses. While laboratory-based studies can offer key insights, assessing the ecological relevance of these findings requires field-based approaches. Therefore, we examined the effects of oxazepam, a widely prescribed anxiolytic drug, on the behaviour of a cyprinid fish (the common roach, ) in the wild, combining slow-release exposure implants with continuous tracking via acoustic telemetry.
View Article and Find Full Text PDFPharmacol Biochem Behav
September 2025
Departamento de Psicobiología y Metodología de las Ciencias del Comportamiento, Universidad de Málaga (UMA), Málaga, 29010, Spain; Instituto de Investigación Biomédica de Málaga y Plataforma en Nanomedicina (IBIMA Plataforma BIONAND), Málaga, Spain. Electronic address:
Adolescence is a period of heightened neuroplasticity and vulnerability to environmental insults, including drug exposure. In this study, we investigated the short- and long-term behavioral effects, as well as the long-term hippocampal effects, of chronic cocaine administration during adolescence, along with the potential neuroprotective role of insulin-like growth factor 2 (IGF2) in male C57BL/6J mice. Over 21 days, mice received daily intraperitoneal injections of saline, cocaine, IGF2, or a combination of cocaine and IGF2.
View Article and Find Full Text PDFBiofabrication
September 2025
Institute of Macromolecular Chemistry, Institute of Macromolecular Chemistry Czech Academy of Sciences, Heyrovského nám. 2, 162 06 Prague 6, Prague, Prague, 162 06, CZECH REPUBLIC.
Extensive peripheral nerve injuries often lead to the loss of neurological function due to slow regeneration and limited recovery over large gaps. Current clinical interventions, such as nerve guidance conduits (NGCs), face challenges in creating biomimetic microenvironments that effectively support nerve repair. The developed GrooveNeuroTube is composed of hyaluronic acid methacrylate and gelatin methacrylate hydrogel, incorporating active agents (growth factors and antibacterial agents) encapsulated within an NGC conduit made of 3D-printed PCL grid fibers.
View Article and Find Full Text PDF