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Spreading dynamics has been considered to take place in temporal networks, where temporal interaction patterns between nodes show non-Poissonian bursty nature. The effects of inhomogeneous interevent times (IETs) on the spreading have been extensively studied in recent years, yet little is known about the effects of correlations between IETs on the spreading. In order to investigate those effects, we study two-step deterministic susceptible-infected (SI) and probabilistic SI dynamics when the interaction patterns are modeled by inhomogeneous and correlated IETs, i.e., correlated bursts. By analyzing the transmission time statistics in a single-link setup and by simulating the spreading in Bethe lattices and random graphs, we conclude that the positive correlation between IETs slows down the spreading. We also argue that the shortest transmission time from one infected node to its susceptible neighbors can successfully explain our numerical results.
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http://dx.doi.org/10.1038/s41598-018-33700-8 | DOI Listing |
Behav Brain Res
September 2025
School of Human Sciences, University of Western Australia, Crawley, WA 6009, Australia.
Tinnitus, the auditory perception of sound without an external environmental stimulus, affects 15% of the human population and is associated with hearing loss. Interestingly, anxiety may be a significant risk factor in tinnitus pathophysiology potentially due to underlying common neural circuits of the auditory and limbic systems. The current study aimed to investigate the effects of stress-induced anxiety on tinnitus development in a rat model.
View Article and Find Full Text PDFMol Psychiatry
September 2025
Obstetrics and Gynecology Hospital of Fudan University, Shanghai Key Lab of Reproduction and Development, Shanghai Key Lab of Female Reproductive Endocrine Related Diseases, Shanghai, China.
Dramatic drop in reproductive hormone, especially estrogen level, from pregnancy to postpartum period is known to contribute to postpartum depression (PPD), but the underlying mechanism and the role of the estrogen receptors (ERs) in this process were unclear. Here, we used an estrogen-withdrawal-induced PPD model following hormone simulated pregnancy (HSP) in female Sprague-Dawley rats to induce depressive-like behaviors. After estrogen withdrawal, we observe an up-regulation of astrocyte-specific potassium channel (Kir4.
View Article and Find Full Text PDFRespir Med
September 2025
Centre of Excellence in Treatable Traits, College of Health, Medicine and Wellbeing, University of Newcastle, New Lambton Heights, NSW, Australia; Asthma and Breathing Research Program, Hunter Medical Research Institute, New Lambton Heights, NSW, Australia; Department of Respiratory and Sleep Medici
Background: The benefits of oral corticosteroid (OCS) stewardship approaches -including monoclonal antibody treatments for severe asthma- on reducing toxic OCS exposure and related comorbidities such as depression and anxiety require real-world evaluation.
Methods: This real-world observational study investigated OCS exposure and associated complications over 24 months in patients enrolled in the Australian Mepolizumab Registry (n = 412).
Results: Patients were median age 59 years, 58 % were female.
J Dairy Sci
September 2025
State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun 130062, China. Electronic address:
Subclinical ketosis (SCK) in periparturient cows is associated with gut microbiota dysbiosis and energy metabolism disorders. Although in vitro studies show that free fatty acids (FFA) and BHB impair polymorphonuclear neutrophil (PMN) functions-potentially causing secondary infections-limited in vivo evidence exists. Astragalus polysaccharides (APS) modulate metabolism, immunity, and gut microbiota, but their effects on PMN functions and gut microbiota in SCK cows remain unclear.
View Article and Find Full Text PDFBackground: Anti-tachycardia pacing (ATP) delivered from implantable cardioverter defibrillators (ICDs) provides critically timed pacing pulses to terminate ventricular tachycardia (VT). Physiological pacing through left bundle branch area (LBBA) pacing has emerged as a clinically relevant alternative to induce synchronous activation of the ventricles. The main objective of this study was to compare the efficacy and safety of ATP delivered to an LBBA lead and a conventional RV lead.
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