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Objective: To estimate the natural history of cervical effacement in labor.
Study Design: This is a retrospective cohort study of term, vertex, singletons who reached 10 cm of cervical dilation from 2010 to 2014. Interval-censored regression was used to estimate the median number of hours between changes in effacement (measured in centimeters of the residual cervix) and to estimate the median effacement at a given cervical dilation. Analysis was stratified by parity and labor type.
Results: In total, 7,319 patients were included. Multiparas had faster effacement from 1 cm to complete effacement than nulliparas, but nulliparas were significantly more effaced at each cervical dilation. Patients in spontaneous labor had faster effacement and were significantly more effaced at each centimeter of cervical dilation than those who were induced or augmented. Once active labor was established (>6 cm of cervical dilation), 95% of patients had an effacement of 1 cm or less. By 8 cm of cervical dilation, 50% of all patients were completely effaced.
Conclusion: There is a wide range in the normal length of time for the progression of cervical effacement. However, once a patient is in active labor, 95% of patients have effaced to 1 cm or less.
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http://dx.doi.org/10.1055/s-0038-1645858 | DOI Listing |
Objectives: Cervical cancer is a serious threat to women's life and health and has a high mortality rate. Colposcopy is an important method for early clinical cervical cancer screening, but the traditional vaginal dilator has problems such as discomfort in use and cumbersome operation. For this reason, this study aims to design an intelligent vaginal dilatation system to automate colposcopy and enhance patient comfort.
View Article and Find Full Text PDFPurpose: The purpose of this document is to review current methods for cervical ripening and to summarize the effectiveness of these approaches based on appropriately conducted outcomes-based research. This document focuses on cervical ripening in individuals with term, singleton, vertex pregnancies with membranes intact, because this is the population in whom most studies were conducted. For more information on recommended timing of delivery based on maternal, fetal, and obstetric conditions and on labor management, refer to: American College of Obstetricians and Gynecologists (ACOG) Committee Opinion No.
View Article and Find Full Text PDFJMIR Med Inform
September 2025
Department of Hepatobiliary and Vascular Surgery, First Affiliated Hospital of Chengdu Medical College, Chengdu, China.
Background: Primary liver cancer, particularly hepatocellular carcinoma (HCC), poses significant clinical challenges due to late-stage diagnosis, tumor heterogeneity, and rapidly evolving therapeutic strategies. While systematic reviews and meta-analyses are essential for updating clinical guidelines, their labor-intensive nature limits timely evidence synthesis.
Objective: This study proposes an automated literature screening workflow powered by large language models (LLMs) to accelerate evidence synthesis for HCC treatment guidelines.
Front Sociol
August 2025
Laboratory of Anthropology of Contemporary Worlds (LAMC), Faculty of Philosophy and Social Sciences, Institute of Sociology, Université Libre de Bruxelles (ULB), Brussels, Belgium.
Contemporary debates about artificial intelligence (AI) still treat automation as a straightforward substitution of human labor by machines. Drawing on Goffman's dramaturgical sociology, this paper reframes AI in the workplace as rather than automation. We argue that the central-but routinely overlooked-terrain of struggle is symbolic-interactional: workers continuously stage, conceal, and re-negotiate what counts as "real" work and professional competence.
View Article and Find Full Text PDFInt J Gynaecol Obstet
September 2025
Laboratory of Medical Biology-Genetics, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Cervical insufficiency (CI) is characterized by spontaneous dilation of the cervix in the absence of painful uterine contractions in the mid-trimester, leading to premature delivery. It is responsible for up to 20% of second trimester pregnancy losses, mostly <24 weeks. This life-threatening condition for the growing fetus faced during pregnancy is of complex etiology.
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