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Article Abstract
Background: Fasciolosis is an important zoonotic disease affecting the productive performance of farm animals in Egypt.
Aim: The aim of the present study was comparing the ovicidal effect of different extracts as an alcoholic (Methanolic and Ethanolic) and aqueous leaf extracts on non-embryonated and developed eggs.
Materials And Methods: Tested concentrations of extracts ranged from 12.5 to 800 mg/ml. Nitroxynil was used as reference drug with a dose of 100 mg/ml.
Results: alcoholic and aqueous extracts showed a concentration-dependent ovicidal effect on non-embryonated and developed eggs. Based on LC values, water extract showed the highest ovicidal activity since it registered the lowest values of 2.6 mg/ml on non-embryonated eggs. Non-embryonated eggs were more susceptible to aqueous extract than developed eggs. On the other hand, the developed eggs were more susceptible to ethanolic extract than non-embryonated eggs even the lowest LC (12.38 mg/ml).
Conclusion: leaf extracts especially aqueous extract could be a promising step in the field of controlling fascioliasis. Further, studies are needed to enlighten the therapeutic potential of extracts in treating infection.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891877 | PMC |
| http://dx.doi.org/10.14202/vetworld.2018.215-220 | DOI Listing |
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