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Purpose: The optimal radiofrequency (RF) power and lesion duration using contact force (CF) sensing catheters for atrial fibrillation (AF) ablation are unknown. We evaluate 50 W RF power for very short durations using CF sensing catheters during AF ablation.
Methods: We evaluated 51 patients with paroxysmal (n = 20) or persistent (n = 31) AF undergoing initial RF ablation.
Results: A total of 3961 50 W RF lesions were given (average 77.6 ± 19.1/patient) for an average duration of only 11.2 ± 3.7 s. As CF increased from < 10 to > 40 g, the RF application duration decreased from 13.7 ± 4.4 to 8.6 ± 2.5 s (p < 0.0005). Impedance drops occurred in all ablations, and for patients in sinus rhythm, there was loss of pacing capture during RF delivery suggesting lesion creation. Only 3% of the ablation lesions were at < 5 g and 1% at > 40 g of force. As CF increased, the force time integral (FTI) increased from 47 ± 24 to 376 ± 102 gs (p < 0.0005) and the lesion index (LSI) increased from 4.10 ± 0.51 to 7.63 ± 0.50 (p < 0.0005). Both procedure time (101 ± 19.7 min) and total RF energy time (895 ± 258 s) were very short. For paroxysmal AF, the single procedure freedom from AF was 86% at 1 and 2 years. For persistent AF, it was 83% at 1 year and 72% at 2 years. There were no complications.
Conclusions: Short duration 50 W ablations using CF sensing catheters are safe and result in excellent long-term freedom from AF for both paroxysmal and persistent AF with short procedure times and small amounts of total RF energy delivery.
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http://dx.doi.org/10.1007/s10840-018-0322-6 | DOI Listing |
PLoS One
September 2025
Department of Microbiology and Parasitology, Faculty of Biology - Aquatic One Health Research Center (iARCUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain.
Uropathogenic Escherichia coli (UPEC) are among the first pathogens to colonise in catheter and non-catheter-associated urinary tract infections. However, these infections are often polymicrobial, resulting in multi-species infections that persist by forming biofilms. Living within these highly antimicrobial tolerant communities, bacteria can establish intra- and inter-specific interactions, including quorum sensing (QS)-mediated signalling mechanisms, which play a key role in biofilm establishment and maturation.
View Article and Find Full Text PDFNat Mater
September 2025
State Key Laboratory of Optoelectronic Materials and Technologies, Guangdong Province Key Laboratory of Display Material and Technology, School of Electronics and Information Technology, Sun Yat-sen University, Guangzhou, China.
Small-scale magnetically actuated catheters capable of remote active navigation have promising applications in minimally invasive surgeries. However, existing fabrication techniques hinder their integration with multimodal sensing components, especially since embedding rigid electronic components within the catheters may diminish their flexibility and controllability. Here we report a magnetically actuated bioelectronic catheter with the in situ multiplexed biosensing of multiple types of metabolite or ion simultaneously.
View Article and Find Full Text PDFJ Infus Nurs
September 2025
Author Affiliations: Nursing Department, Universidade Federal de Santa Catarina, Florianópolis, Santa Catarina, Brazil (Fernandes Albeirice da Rocha, Zaghi Vitor, and Kuerten Rocha); Health and Services Department, Instituto Federal de Santa Catarina, Joinville, Santa Catarina, Brazil (Fernandes Al
The aim of the study was to evaluate the effectiveness of virtual reality in reducing pain and procedure-related distress during peripheral intravenous catheter (PIVC) insertion in children. A 2-arm, randomized, parallel-group clinical trial compared virtual reality with standard care. Children aged 4 to 14 years requiring an elective PIVC were randomly assigned (1:1) to virtual reality with a relaxing ocean film (intervention group) or standard care (control group).
View Article and Find Full Text PDFEinstein (Sao Paulo)
September 2025
Department of Pediatrics, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
Objective: To analyze the impact of a serious immersive virtual reality game on the physiological and behavioral aspects of pain during peripheral venous access or central catheter puncture in children and adolescents with cancer.
Methods: This was a longitudinal intervention study that included 50 children and adolescents undergoing cancer therapy and peripheral venipuncture or venous catheter puncture (totally implanted or central venous catheter) at two independent time points (control and experimental intervention). The intervention consisted of playing a serious immersive virtual reality game with three-dimensional goggles and a Bluetooth controller.
J Racial Ethn Health Disparities
September 2025
Division of Pediatric Surgery, Department of Surgery, University of Rochester Medical Center, 601 Elmwood Ave, Box SURG, Rochester, NY, USA.
Background: The purpose of this study was to use factor analysis to explore potential underlying dimensions that explain associations between social determinants of health (SDoH), operationalized as Social Deprivation Index (SDI) and Area Deprivation Index (ADI) scores and other neighborhood characteristics, and postoperative outcomes in pediatric patients with simple appendicitis.
Methods: We retrospectively reviewed all children (age < 18 years) who underwent an appendectomy for simple appendicitis at our institution (January 2015-December 2021). Patients were identified and patient demographics, clinicopathologic factors, and postoperative outcomes were abstracted from the American College of Surgeons National Surgical Quality Improvement Program Pediatric (NSQIP-P) institutional dataset.