Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
This critical review of electrochemical biosensors allowing direct detection of nucleic acid targets reports on different transduction pathways and their latest breakthroughs. A classification of the various strategies based on the nature of the electrochemical transduction is established to emphasize the efficiency of each of them. It provides an overall picture of the detection limit of the various approaches developed during the last two decades. Graphical Abstract Detection limits evolutions of electrochemical DNA biosensors.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s00216-017-0377-8 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Novel mode of heart and lung machine for real-time identification of cerebral autoregulation impairments during cardiac surgery with cardiopulmonary bypass: prospective observational study.
Minerva Anestesiol
September 2025
Department of Cardiac, Thoracic and Vascular Surgery, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Background: Postoperative cognitive dysfunction (POCD) occurs in 20% to 80% of patients following cardiac surgical interventions. The incidence of delirium is from 20% to 50%. Impaired cerebral autoregulation (CA) during cardiopulmonary bypass (CPB) contributes to these issues.
View Article and Find Full Text PDFRational Hapten Design for the Immunochromatographic Assay of Yohimbine, an Emerging Adulterant in Food.
J Agric Food Chem
September 2025
Guangdong Provincial Key Laboratory of Food Quality and Safety/Nation-Local Joint Engineering Research Center for Machining and Safety of Livestock and Poultry Products, South China Agricultural University, Guangzhou 510642, China.
Adulterated yohimbine (YHB) in food poses a risk to public health, making it imperative to develop fast and sensitive detection methods. In this study, computational-chemistry-based prediction was employed to design YHB haptens for generating the high-affinity monoclonal antibody Yohi-4A7, which exhibited an optimal half-inhibitory concentration (IC) of 1.69 ng/mL against YHB.
View Article and Find Full Text PDFRevolutionizing meropenem detection: novel OVA-PtNP nanoenzymes for clinical and environmental safety.
Analyst
September 2025
Department of Pharmaceutical Analysis, School of Pharmacy, Fujian Medical University, Fuzhou 350108, P. R. China.
: The objective of this study is to develop a straightforward and expeditious clinical detection method for meropenem. This study aims to introduce an innovative nanoenzyme design, thereby broadening the application of platinum nanomaterials in biological detection. It seeks to facilitate the portable detection of meropenem using commercial software.
View Article and Find Full Text PDFMultilayered Sandwich Structure Sensor: Confinement-Mediated HO Enrichment Strategy for Ultrasensitive and Long-term Stable Prostate Cancer Biomarker Detection.
Small
September 2025
School of Chemistry and Chemical Engineering, Guangxi Key Laboratory of AI-Driven Zero-Carbon Technologies, Key Laboratory of New Low-carbon Green Chemical Technology Education Department of Guangxi Zhuang Autonomous Region, Guangxi University, Nanning, 530004, China.
Sarcosine (Sar), a critical potential biomarker for prostate cancer (PCa), is primarily detected via enzyme cascade reactions involving sarcosine oxidase (SOx) and peroxidase. Nevertheless, the intermediate product hydrogen peroxide (HO) tends to diffuse to the bulk solution phase without entering subsequent reaction, leading to suboptimal detection sensitivity and compromised analytical performance. To tackle this challenge, a multilayered sandwich nanozyme cascade sensor (designated as Cu-MOF/Rf@BDC) is proposed through a confinement-mediated HO enrichment strategy.
View Article and Find Full Text PDFPlasma-Tunable Metasurfaces for SERS Nanosensing of Hazardous Chemicals.
Small
September 2025
Jožef Stefan Institute, Jamova cesta 39, Ljubljana, SI-1000, Slovenia.
The demand for rapid, field-deployable detection of hazardous substances has intensified the search for plasmonic sensors with both high sensitivity and fabrication simplicity. Conventional approaches to plasmonic substrates, however, often rely on lithographic precision or complex chemistries limiting scalability and reproducibility. Here, a facile, one-step synthesis of vertically aligned 2D nanosheets composed of intergrown CuO/CuO crystallites is presented, fabricated via oxygen plasma discharge on copper substrates.
View Article and Find Full Text PDF