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Article Abstract

Patients with high risk myelodysplastic syndromes (MDS) and acute myelogenous leukemia (AML) are commonly older with multiple co-morbidities, rendering them unsuitable for intensive induction chemotherapy or transplantation. We report preliminary cellular immune profiling of four cases receiving sequential clofarabine and lenalidomide for high risk MDS and AML in a phase I study. Our results highlight the potential of immune profiling for monitoring immune-modifying agents in high risk MDS and AML.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402630PMC
http://dx.doi.org/10.1016/j.lrr.2017.04.003DOI Listing

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