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Deducing the state of a dynamical system as a function of time from a limited number of concurrent system state measurements is an important problem of great practical utility. A scheme that accomplishes this is called an "observer." We consider the case in which a model of the system is unavailable or insufficiently accurate, but "training" time series data of the desired state variables are available for a short period of time, and a limited number of other system variables are continually measured. We propose a solution to this problem using networks of neuron-like units known as "reservoir computers." The measurements that are continually available are input to the network, which is trained with the limited-time data to output estimates of the desired state variables. We demonstrate our method, which we call a "reservoir observer," using the Rössler system, the Lorenz system, and the spatiotemporally chaotic Kuramoto-Sivashinsky equation. Subject to the condition of observability (i.e., whether it is in principle possible, by any means, to infer the desired unmeasured variables from the measured variables), we show that the reservoir observer can be a very effective and versatile tool for robustly reconstructing unmeasured dynamical system variables.
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http://dx.doi.org/10.1063/1.4979665 | DOI Listing |
Hum Reprod Open
August 2025
Department of Clinical Laboratory, Institute of Translational Medicine, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Study Question: Do social determinants of health (SDoH) influence the age at menopause among women?
Summary Answer: In our study, adverse SDoH, particularly family low income-to-poverty ratio (PIR), low education level, and the marital status of being widowed, are associated with earlier age at menopause.
What Is Known Already: Some prior studies have considered certain SDoH variables (such as educational attainment and marital status) as potential factors influencing age at menopause, but systematic evidence clearly defining the relationship between multidimensional SDoH and menopausal age remains lacking.
Study Design Size Duration: This cross-sectional analysis included 6083 naturally menopausal women from 10 cycles (1999-2018) of the United States National Health and Nutrition Examination Survey (NHANES) and excluded cases of surgical menopause.
Biometrika
December 2024
Department of Biostatistics, Johns Hopkins University, 605 N Wolfe Street, Baltimore, Maryland 21215, U.S.A.
This article addresses the asymptotic performance of popular spatial regression estimators of the linear effect of an exposure on an outcome under spatial confounding, the presence of an unmeasured spatially structured variable influencing both the exposure and the outcome. We first show that the estimators from ordinary least squares and restricted spatial regression are asymptotically biased under spatial confounding. We then prove a novel result on the infill consistency of the generalized least squares estimator using a working covariance matrix from a Matérn or squared exponential kernel, in the presence of spatial confounding.
View Article and Find Full Text PDFBMC Med Res Methodol
September 2025
Department of Primary Care and Population Health, UCL, London, UK.
Background: The increased availability of large-scale longitudinal data offers important opportunities to assess the causal effects of health interventions. In this setting, Instrumental Variable (IV) approaches have the potential to reduce the risk of bias from confounding due to unmeasured variables. However, there has been a lack of attention given to the development of IV approaches in settings when both the instrument and the potential confounders vary over time.
View Article and Find Full Text PDFThis study explored the differences in circulating cytokines between sexes and age and their association with the pathogenesis of coronary artery disease ( CAD ) in order to identify populations suitable for anti-inflammatory treatment. Methods:This retrospective study included hospitalized patients who underwent coronary angiography between October 2022 and November 2024. The selected participants were grouped by age and sex to compare differences in circulating inflammatory cytokine levels and CAD occurrence.
View Article and Find Full Text PDFIEEE Trans Cybern
August 2025
In this article, the anti-disturbance switching control approach is proposed for silicon single crystal growth systems with unmeasured states. Initially, the silicon single crystal growth systems are modeled by using the geometrical models of meniscus section, hydrodynamic and heat transfer process of silicon single crystal growth. Since numerous unmeasurable state variables exist in systems and the growth equipments are affected by external and internal disturbances, consideration is given to employing the output feedback control scheme and disturbance observer method in the construction of the anti-disturbance switching controller.
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