Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Background: The purpose of this study was to compare the effects of high and low velocity knee extension training on changes in muscle strength and mobility status in high-functioning older adults.
Methods: Twenty-six (16 female, 10 male) older adults (mean age of 65) were randomized to either 6weeks of low velocity resistance training (LVRT) performed at 75°/s or high velocity resistance training (HVRT) performed at 240°/s. Both groups performed 3 sets of knee extension exercises at maximal effort, 3 times a week. Muscle strength was assessed through a range of testing velocities on an isokinetic dynamometer. Mobility status was assessed with the short physical performance battery (SPPB) and myosin heavy chain (MyHC) transcript levels were quantified via qRT-PCR.
Results: From baseline to post-training, there were several significant (P<0.05) differences in muscle strength and functional characteristics in LVRT (n=13) and HVRT (n=13) groups. From baseline to post-training, MyHC-α mRNA and MyHC-IIa mRNA showed a significant (P<0.05) increase within HVRT but MyHC-IIx mRNA did not change significantly. Our results demonstrate HVRT provides a greater number of muscular enhancements when compared to LVRT, particularly under conditions of high velocity muscle contraction.
Conclusion: HVRT is emerging as the optimal training stimulus for the older adult. The present study demonstrates, in addition to increased strength and functional outcomes, HVRT elicits a potentially therapeutic (i.e., slow to fast) transcriptional response in MyHC.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.exger.2017.02.072 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
High-Intensity Exercise and Hippocampal Integrity in Adults With Cannabis Use Disorder: A Randomized Clinical Trial.
JAMA Psychiatry
September 2025
School of Psychological Sciences, Monash University, Melbourne, Victoria, Australia.
Importance: Cannabis is the most commonly used illicit drug, with 10% to 30% of regular users developing cannabis use disorder (CUD), a condition linked to altered hippocampal integrity. Evidence suggests high-intensity interval training (HIIT) enhances hippocampal structure and function, with this form of physical exercise potentially mitigating CUD-related cognitive and mental health impairments.
Objective: To determine the impact of a 12-week HIIT intervention on hippocampal integrity (ie, structure, connectivity, biochemistry) compared with 12 weeks of strength and resistance (SR) training in CUD.
Bone Stress Injuries in Endurance Athletes: A Review of Risk Factors, Screening and Evaluation Pearls, Preventive Strategies, and Evidence-Based Management Approaches.
Curr Sports Med Rep
September 2025
Family Medicine, Uniformed Services University, Family and Sports Medicine, Travis AFB, CA.
Bone stress injury is a common musculoskeletal condition presenting with insidious bony pain that is progressive and occurs with a number of intrinsic or extrinsic risk factors, particularly with a recent change in training. When elicited, the presence of bony tenderness remains the most important component of the physical exam, although reproduction at deeper sites is a challenge and requires a high index of suspicion and imaging for diagnosis. MRI should be utilized as the gold standard for diagnosis, grading, and return-to-sport timing prognosis when available, with plain radiographs used as first-line imaging.
View Article and Find Full Text PDFPhase Crosslinking Strategy to Construct Impact-Resistant and Buffer-Enhanced Bilayer Hydrogels with High Interfacial Adhesion.
Small
September 2025
College of Science, Nanjing Forestry University, Nanjing, 210037, China.
Inspired by the rigid exoskeleton and elastic inner tissues of crustaceans, a bilayer gel integrating high-strength rigidity and soft cushioning with high interfacial adhesion (1060 ± 40 J m ) is developed via a stepwise solid-liquid phase crosslinking strategy. Herein, a prefrozen high-concentration polyvinyl alcohol (PVA) solution forms a solid-state structural framework, while a subsequently cast low-concentration PVA solution generates a flexible layer. Partial thawing of the frozen gel during casting triggers molecular chain interpenetration at the interface, synergistically enhanced by controlled molecular penetration, freeze-thaw cycles, and salt-induced crystallization.
View Article and Find Full Text PDFFeasibility and efficacy of exercise training on sleep symptoms and comorbidities in narcolepsy type 1: a prospective interventional study.
Sleep
September 2025
Center for Sleep Medicine, Hospices Civils de Lyon, Lyon 1 University, Lyon, F-69000, France.
Current treatments for narcolepsy type 1 (NT1) have little impact on psychiatric, cognitive and metabolic comorbidities. Here, we evaluated the feasibility, safety and efficacy of a prospective Exercise Training (ET) program on sleep-related symptoms and comorbidities in NT1. Sedentary adult with NT1 participated in a 6-week supervised ET program followed by a 18-week self-directed program.
View Article and Find Full Text PDFEffects of Combined Exercise Training on Modulating Fine Particulate Matter-Induced Skeletal Muscle Damage in Offspring Gestationally Exposed.
J Cachexia Sarcopenia Muscle
October 2025
Department of Sports Science, College of Natural Science, Jeonbuk National University, Jeonju, Republic of Korea.
Background: Fine particulate matter has developmental toxicity, and midgestation is an important period for the development of foetal skeletal muscle. The ability of exercise to modulate skeletal muscle damage in mice exposed to PM during gestation remains unclear.
Methods: Pregnant C57BL/6 mice were exposed to 50 μg/m PM for 2 h on five consecutive days starting at embryonic day 12.