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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192131 | PMC |
| http://dx.doi.org/10.1128/AAC.01962-16 | DOI Listing |
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Genomic analysis of Klebsiella pneumoniae high-risk clone ST11 co-harbouring MCR-1.27 and KPC-2 recovered at a paediatric oncologic hospital in the Brazilian Amazon region.
J Glob Antimicrob Resist
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Laboratório de Biologia Molecular, Seção de Bacteriologia e Micologia, Instituto Evandro Chagas (IEC), Brazilian Ministry of Health, Ananindeua, Brazil; Program in Epidemiology and Health Surveillance (PPGEVS), Instituto Evandro Chagas (IEC), Ananindeua, Brazil. Electronic address: daniellemurici
Article Synopsis
- * Researchers used methods like antibiotic susceptibility tests and whole genome sequencing to characterize the isolate, revealing it as extensively drug-resistant and belonging to a high-risk genetic clone associated with multiple resistance genes.
- * The findings highlight the urgent need for improved surveillance and research on antibiotic resistance, particularly in vulnerable areas like the Amazon, to combat the threat posed by these resistant bacterial strains.
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University of Health Sciences Gülhane Faculty of Medicine, Department of Medical Microbiology, Ankara, Turkey.
Infections caused by multi drug-resistant gram-negative bacilli are increasingly reported worldwide. Colistin, tigecycline and aminoglycosides are almost the only and last choice antibiotics in the treatment of infections caused by carbapenem-resistant Enterobacterales members. Ceftazidime-avibactam is a novel antibiotic combination consisting of a broad-spectrum cephalosporin and avibactam with good antimicrobial activity against carbapenem-resistant Enterobacterales members.
View Article and Find Full Text PDFMolecular and Phenotypic Characterization of a Multidrug-Resistant Coproducing OXA-232 and MCR1.1 in Argentina.
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Cátedra de Microbiología Clínica, Laboratorio de Bacteriología, Departamento de Bioquímica Clínica, Facultad de Farmacia y Bioquímica, Hospital de Clínicas José de San Martín, INFIBIOC, Universidad de Buenos Aires, Buenos Aires, Argentina.
The spread of arbapenem-resistant Enterobacterales has raised concern in clinical settings due to the limited therapeutic options available. OXA-48-like enzymes are still sporadic in South America. The aim of this study was to characterize a multidrug-resistant isolate from a hospitalized patient in Buenos Aires city.
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Front Microbiol
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Área de Microbiología, Departamento de Biología Funcional, Universidad de Oviedo, Oviedo, Spain.
Colistin is a last-resort antibiotic in fighting severe infections caused by multidrug resistant Gram negative pathogens in hospitals. Zoonotic bacteria acquire colistin resistance in animal reservoirs and mediate its spread along the food chain. This is the case of non-typhoid serovars of .
View Article and Find Full Text PDFCoproduction of Tet(X7) Conferring High-Level Tigecycline Resistance, Fosfomycin FosA4, and Colistin Mcr-1.1 in Escherichia coli Strains from Chickens in Egypt.
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May 2021
Laboratory of Food Microbiology and Hygiene, Graduate School of Integrated Sciences for Life, Hiroshima University, Higashihiroshima, Japan
The plasmid-mediated (X7) conferring high-level tigecycline resistance was identified in five -positive strains (ST10 [ = 3] and ST155 [ = 2]) isolated from chickens in Egypt. Two fosfomycin-resistant -carrying IncFII plasmids (∼79 kb in size) were detected. Transposase IS (IS family) is syntenic with (X7) in all isolates, suggesting its role in the mobilization of (X7).
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