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Introduction: Cerebrospinal Fluid (CFF) fistulae are repaired endoscopically with varying degrees of success around the world. Large series are still uncommon, and the results varied primarily because of the different techniques by different surgeons and also because of a variation in the patient profile in each series, for example, many series deal primarily with traumatic CSF leaks where the defects are larger and outcomes poorer.
Aim: To analyse the surgical outcomes of Endoscopic CSF rhinorrhea closure.
Materials And Methods: This is a series of 34 cases operated upon primarily by one surgeon in two different centres over a period of 10 years.
Results: Of the 34 cases, 76% of the patients were women. Among the patients only 20.6% patients had a history of trauma preceding the CSF leak. The most common site of leak was in the fovea ethmoidalis in 19 (55.8%) followed by 10 (29.4%) in the cribriform plate. An overlay technique of placing the multiple layers of fascia and mucosa was used in 26 (76.5%) patients and underlay technique in the remaining. Postoperative lumbar drain was used in all patients.
Conclusion: Based on the treatment outcome of the 34 patients, it can be concluded that the success rate of a single endoscopic procedure in our experience is 97% and 100% following the second. Endoscopic approach for closure of CSF leak is safe with minimal complications and little morbidity.
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http://dx.doi.org/10.7860/JCDR/2016/18903.8390 | DOI Listing |
Otol Neurotol
August 2025
Department of Otolaryngology-Head and Neck Surgery, Indiana University School of Medicine.
Objective: Determine if class 3, morbid obesity (body mass index, BMI >40 kg/m2) patients have increased risk of complications following middle cranial fossa (MCF) repairs of spontaneous cerebrospinal fluid leaks (sCSF-Ls).
Study Design: Retrospective cohort.
Setting: Tertiary academic.
Laryngoscope
September 2025
Department of Otolaryngology-Head and Neck Surgery, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York, USA.
Objectives: Inverted papilloma (IP) is typically a benign sinonasal tumor with a propensity to recur. The surgical treatment of IP arising from the frontal sinus is complicated by proximity to the orbit and skull base. The objective of this study is to describe the surgical challenges when managing this disease and report treatment outcomes in a multicenter cohort.
View Article and Find Full Text PDFMedicine (Baltimore)
August 2025
Department of Orthopedics, The Third Central Hospital of Tianjin, Tianjin, China.
Rationale: Occult cerebrospinal fluid (CSF) leakage after lumbar spine surgery is common; however, cases in which CSF leakage leads to cauda equina tethering are rare and may result in severe neurological symptoms. This study elucidates the diagnostic challenges and management strategies for this rare complication through a representative case report.
Patient Concerns: A 74-year-old man was diagnosed with lumbar spinal stenosis and lumbar disc herniation.
Pract Neurol
September 2025
Headache and Facial Pain Group, University College London Queen Square Institute of Neurology, London, UK.
A 49-year-old woman developed symptoms of syringomyelia 3 years after having presented with spontaneous intracranial hypotension (SIH). She had previously undergone two unsuccessful non-targeted epidural blood patches. The MR scan showed features of cervicothoracic syringomyelia and ongoing intracranial features of SIH.
View Article and Find Full Text PDFCureus
July 2025
Neurosurgery, Hamad Medical Corporation, Doha, QAT.
This systematic review evaluates the management of cerebrospinal fluid (CSF) leaks following traumatic skull base fractures and examines the associated risk of post-traumatic meningitis (PTM). It also critically investigates the debated hypothesis that meningitis may promote spontaneous closure of defects in the dura mater through inflammation-induced healing. A comprehensive literature search was performed using PubMed, Scopus, and the Cochrane Library according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.
View Article and Find Full Text PDF