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[This corrects the article DOI: 10.1371/journal.pgen.1005378.].
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http://dx.doi.org/10.1371/journal.pgen.1006166 | DOI Listing |
Curr Alzheimer Res
September 2025
Department of Neurology, the Wuxi No. 2 People's Hospital, Jiangnan University Medical Center, Wuxi, Jiangsu Province, China.
Introduction: The complement receptor 1 (CR1) gene is identified as the one closely associated with Alzheimer's disease (AD). However, there has been no exploration of the imaging alterations associated with the CR1 gene in AD patients of the Han population. The purpose of this study is to investigate the association between the rs6656401 mutation and neuroimaging variations in Han AD patients.
View Article and Find Full Text PDFWater Res
August 2025
School of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing, China. Electronic address:
Global phosphorus (P) resources are facing a depletion crisis, and pyrolysis of P-rich sewage sludge (SS) offers significant resource potential. Optimizing pyrolysis conditions remains key yet challenging for enhancing P retention and bioavailability. This study conducted a correlation-prediction-causation integrated framework (CPCIF) to investigate how heating temperature (HT), heating rate (HR), and retention time (RT) influence total P enrichment rate (BTPE), relative inorganic P transformation rate (BITP), and relative apatite P transformation rate (BAIP) from SS to biochar during pyrolysis.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
September 2025
Department of Humanities and Social Sciences, Indian Institute of Science Education and Research (IISER) Tirupati, Tirupati City, Andhra Pradesh, India.
Anal Chim Acta
November 2025
School of Pharmacy, Tongji Medical College, Huazhong University of Science & Technology, #13 Hangkong Road, Wuhan, Hubei, 430030, PR China. Electronic address:
Even small deviations in modulation timing (DMT) can cause discrepancies between the originally set modulation period (P) and the actual P in comprehensive two-dimensional gas chromatography (GC × GC) analysis. This study explored the impact of DMT on the accuracy of the second dimensional retention time (t) and the second dimensional retention index (I) calculations and introduced a line detection technology (LDT) based on the Hough Transform to correct DMT-induced t shifts. The correction was achieved by automatically adjusting candidate P values until the slope of the line(s) (CB_line(s)) formed by column bleeding compound peaks in the isothermal section of the contour plot approached zero, thereby determining the actual P.
View Article and Find Full Text PDFBioresour Technol
September 2025
State Key Laboratory of Food Science and Resources, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; School of Biotechnology and Key Laboratory of Industrial Biotechnology Ministry of Education, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, China; International Joint Laboratory on Fo
Recombinant proteins have been widely applied in the food, biomedical, and scientific fields. Prokaryotic expression systems are preferred platforms for recombinant protein production due to their rapid growth and high protein yields. Nevertheless, disparities between recombinant expression environment and native physiological conditions frequently result in protein misfolding, leading to aggregation into non-functional inclusion bodies or proteolytic degradation.
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