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Introduction: To evaluate the effectiveness of QMix solution (Dentsply Tulsa Dental Specialties, Tulsa, OK) on the smear layer using the following irrigation activation techniques: the EndoActivator (EA) system (Dentsply Tulsa Dental Specialties), photon-initiated photoacoustic streaming (PIPS), and an Er:YAG laser with an endodontic fiber tip.
Methods: Sixty-four extracted single-rooted human teeth were decoronated and the canals instrumented with ProTaper (Denstply Maillefer, Ballagues, Switzerland) up to size F4. The canals were irrigated with 5.25% sodium hypochlorite and a saline solution for 1 minute each. The specimens were then divided randomly into 4 experimental and 4 control groups (n = 8) according to the final irrigation activation technique. These groups included group 1, 2.5 mL QMix; group 2, QMix + EA; group 3, QMix + PIPS; and group 4: QMix + Er:YAG. Laser activated distilled water was used as control groups 5, 6, 7, and 8. Teeth were split longitudinally, and specimens were observed under a scanning electron microscope. Images were taken at the coronal, middle, and apical thirds of the teeth at a magnification of 1000× and were scored in the presence of the smear layer. Data were analyzed with Kruskal-Wallis and Mann-Whitney U tests.
Results: The highest scores were found in the apical third of all groups (P < .05). The QMix + Er:YAG group removed the smear layer more effectively than the nonactivated QMix group in the apical third (P < .05). The QMix + EA group removed the smear layer significantly in all thirds of the teeth when compared with the nonactivated QMix group (P < .05). The QMix + PIPS group showed a significantly better effect than the QMix group in the coronal third (P < .05).
Conclusions: The EA and Er:YAG laser enhanced the smear layer removal ability of QMix in the apical thirds of the canals. QMix removed more smear layer in the coronal thirds when activated with the PIPS technique.
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http://dx.doi.org/10.1016/j.joen.2016.04.022 | DOI Listing |
J Dent
September 2025
Department of Restorative Dentistry, Faculty of Dentistry, Malaya University, Kuala Lumpur, Malaysia. Electronic address:
Objectives: to evaluate the effect of smear-layer deproteinization using papain gel and SPRG-adhesive on marginal-gap, anti-demineralization of enamel and dentin after chemical pH cycling and assess acid-base resistance zone (ABRZ) characteristics.
Methods: Cylindrical cavities were prepared cervically in thirty-two extracted premolars. Teeth were divided into two pretreatment groups (n=16); deproteinization with papain enzyme gel (Papacarie Due, Brazil) for 60 second, and no-deproteinization.
J Endod
August 2025
Department of Bioscience Research, College of Dentistry, University of Tennessee Health Science Center, Memphis, TN, USA; Department of Endodontics(,) College of Dentistry, The University of Tennessee Health Science Center, Memphis, Tennessee; Department of Physiology, College of Medicine, Universit
Introduction: To investigate the combined use of laser, nanobubble water (NB-HO), and calcium hydroxide (Ca(OH)) for endodontic disinfection, particularly in regenerative endodontic cases where maximum effectiveness is needed.
Methods: Canal of human teeth were prepared, sterilized and inoculated with Enterococcus faecalis (E. faecalis).
BMC Oral Health
August 2025
Department of Periodontology, Faculty of Dentistry, Gazi University, Ankara, Türkiye.
Background: Root surface biomodification (RSB) enhances tissue attachment by removing the smear layer, facilitating collagen fibril formation, and promoting clot formation and stabilization. This study aimed to evaluate the efficacy of injectable platelet-rich fibrin (i-PRF), an autologous blood product, as a potential adjunct to ethylenediaminetetraacetic acid (EDTA) for RSB in gingival fibroblast attachment and proliferation in vitro.
Methods: Dentin discs (4 mm in diameter) underwent root surface debridement to remove damaged cementum.
Shanghai Kou Qiang Yi Xue
June 2025
Department of Stomatology, Chifeng University Affiliated Hospital. Chifeng 024000, China. E-mail:
Purpose: To evaluate the effects of Er:YAG laser combined with NaClO on the removal of root canal taint layer, calcium hydroxide clearance and dentin microhardness.
Methods: A total of 318 single-rooted extracted teeth collected from March 2021 to January 2024 were selected, the 13 mm root was taken and mechanically prepared and randomly divided into three groups, with 106 teeth in each group. The control group was rinsed with NaClO, the experimental group 1 was rinsed with NaClO combined with ultrasonic washing, and the experimental group 2 was treated with Er:YAG laser on the basis of NaClO.
J Conserv Dent Endod
August 2025
Department of Orthodontics and Dentofacial Orthopedics, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Pune, India.
Aim: The aim of the study was to evaluate the antimicrobial properties of calcium hydroxide (CH)-loaded polylactic-co-glycolic acid (PLGA) nanoparticles (NPs) and CH when used as an intracanal medicament (ICM).
Methods: Adhering guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-analysis, the review was registered in the Prospective Registration of Systematic Review-CRD42023454265. Databases from January 2000 to December 2023 were examined for studies evaluating the various properties of CH-loaded PLGA NPs compared to conventional ICM-CH.